SCHEMBL1750368

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1750051	1.00	RIPK1 (0.46)	RIPK1PDE5APDE4APDE1APDE1B
	SCHEMBL1750369	1.00	RIPK1 (0.46)	RIPK1PDE5APDE4APDE1APDE1B
	SCHEMBL1750239	0.91	RIPK1 (0.46)	RIPK1PDE5APDE4APDE1APDE1B
	SCHEMBL3045877	0.88	RIPK1 (0.42)	RIPK1PDE5APDE4APDE1APDE1B
	SCHEMBL3033937	0.88	RIPK1 (0.42)	RIPK1PDE5APDE4APDE1APDE1B
	SCHEMBL1752110	0.88	RIPK1 (0.42)	RIPK1PDE5APDE4APDE1APDE1B
	SCHEMBL1750994	0.83	RIPK1 (0.41)	RIPK1HDAC11
	SCHEMBL1750995	0.83	RIPK1 (0.41)	RIPK1HDAC11
	SCHEMBL1750125	0.82	RIPK1 (0.41)	RIPK1PDE5APDE4APDE1APDE1B
	SCHEMBL1750671	0.81	RIPK1 (0.41)	RIPK1PDE5APDE4APDE1APDE1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.