SCHEMBL1750994

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1750995	1.00	RIPK1 (0.41)	RIPK1HDAC11HSD11B1CCR3MMP1
	SCHEMBL1750890	0.88	RIPK1 (0.40)	RIPK1HDAC11CCR3MCHR1HTR2C
	SCHEMBL1750051	0.83	RIPK1 (0.46)	RIPK1HDAC11
	SCHEMBL1750369	0.83	RIPK1 (0.46)	RIPK1HDAC11
	SCHEMBL1750368	0.83	RIPK1 (0.46)	RIPK1HDAC11
	SCHEMBL20118125	0.81	ALDH1A1 (0.51)	RIPK1
	SCHEMBL3033937	0.81	RIPK1 (0.42)	RIPK1HDAC11
	SCHEMBL3045877	0.81	RIPK1 (0.42)	RIPK1HDAC11
	SCHEMBL1752110	0.81	RIPK1 (0.42)	RIPK1HDAC11
	SCHEMBL1750080	0.78	BACE1 (0.41)	RIPK1HDAC11HSD11B1CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.