Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416900 | 0.81 | ALDH1A1 (0.45) | TRPA1NFE2L2ALDH1A1TSHRMAOB | |
| SCHEMBL28895712 | 0.81 | — | — | |
| SCHEMBL6681380 | 0.73 | LMNA (0.62) | ALDH1A1LMNAL3MBTL1MAPTMEN1 | |
| SCHEMBL28122118 | 0.73 | NFE2L2 (0.46) | TRPA1NFE2L2ALDH1A1LMNAHDAC8 | |
| SCHEMBL16447076 | 0.73 | NFE2L2 (0.46) | TRPA1NFE2L2ALDH1A1LMNAHDAC8 | |
| SCHEMBL1302 | 0.71 | ALDH1A1 (0.53) | TRPA1NFE2L2ALDH1A1TSHRMAOB | |
| SCHEMBL28730003 | 0.70 | — | — | |
| SCHEMBL4572237 | 0.70 | — | — | |
| SCHEMBL1009581 | 0.70 | TSHR (0.52) | TRPA1NFE2L2ALDH1A1TSHRMAOB | |
| SCHEMBL8474848 | 0.70 | TRPA1 (0.64) | TRPA1NFE2L2ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221147-B2 | Heterocyclic compounds with working memory enhancing activity | RED BULL GMBH (AT) | 2019-03-05 | — | — | US | disclosed |
| EP-2985279-B1 | Heterocyclic compounds with working memory enhancing activity | RED BULL GMBH (AT) | 2017-08-02 | — | — | EP | disclosed |
| US-20170174642-A1 | HETEROCYCLIC COMPOUNDS WITH WORKING MEMORY ENHANCING ACTIVITY | COGMOTIV FLEXCO (AT) | 2017-06-22 | — | — | US | disclosed |
| WO-2016023997-A1 | HETEROCYCLIC COMPOUNDS WITH WORKING MEMORY ENHANCING ACTIVITY | RED BULL GMBH (AT) | 2016-02-18 | — | — | WO | disclosed |
| EP-2985279-A1 | Heterocyclic compounds with working memory enhancing activity | Red Bull GmbH (AT) | 2016-02-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174642-A1 | HETEROCYCLIC COMPOUNDS WITH WORKING MEMORY ENHANCING ACTIVITY | TAAR1, ACHE, RIF1 | TRPA1 1047/4885NFE2L2 54/4885ALDH1A1 384/4885 |
| US-10221147-B2 | Heterocyclic compounds with working memory enhancing activity | TAAR1, ACHE, RIF1 | TRPA1 1047/4885NFE2L2 54/4885ALDH1A1 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.