SCHEMBL17508555

SCHEMBL17508555

Clc1ccccc1C1(c2cc(-c3ccccc3)c(-c3ccccc3)cc2Cl)N=C(c2ccccc2)C(c2ccccc2)=N1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.39
TAAR1 Q96RJ0 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CHRM1 P11229 1/20 0.33
PKM P14618 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MAPK10 P53779 1/20 0.32
CCNE2 O96020 1/20 0.32
CCNE1 P24864 1/20 0.32
CDK2 P24941 1/20 0.32
CSNK2A1 P68400 2/20 0.31
PDK2 Q15119 1/20 0.31
PTGS2 P35354 2/20 0.31
PTGS1 P23219 1/20 0.31
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30
OPRK1 P41145 2/20 0.30
PDE4D Q08499 2/20 0.30
SMARCA2 P51531 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL82274 0.73 TAAR1 (0.40) CYP2A6TAAR1ALDH1A1HTTCRHBP
SCHEMBL12575342 0.70 TAAR1 (0.45) CYP2A6TAAR1ALDH1A1CHRM1HTT
SCHEMBL197098 0.70 MTOR (0.39) TAAR1ALDH1A1ADRA1A
SCHEMBL11212021 0.68 KDM4E (0.41) ALDH1A1
SCHEMBL3757997 0.67 CRHBP (0.36) CYP2A6TAAR1ALDH1A1CRHBPCRHR2
SCHEMBL29403344 0.66 CYP2A6 (0.36) CYP2A6TAAR1ALDH1A1PDK2CRHBP
SCHEMBL356036 0.66 CYP2A6 (0.36) CYP2A6TAAR1ALDH1A1PDK2CRHBP
SCHEMBL80380 0.65 CHRM1 (0.41) ALDH1A1CHRM1PKMHTTNPSR1
SCHEMBL8665932 0.64 IDO1 (0.37) CYP2A6ALDH1A1CHRM1SLC6A3
SCHEMBL491126 0.64 CYP2A6 (0.41) CYP2A6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160039188-A1 TRANSFER MATERIAL, SUBSTRATE WITH TRANSFER LAYER, TOUCH PANEL, MANUFACTURING METHODS THEREFOR, AND INFORMATION DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-02-11 US disclosed