SCHEMBL12575342

SCHEMBL12575342

CC1(c2ccccc2Cl)N=C(c2ccccc2)C(c2ccccc2)=N1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.45
ALDH1A1 P00352 4/20 0.40
CYP2A6 P11509 1/20 0.38
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
HSD11B1 P28845 1/20 0.34
HTT P42858 1/20 0.33
BACE1 P56817 1/20 0.33
LMNA P02545 2/20 0.32
TSHR P16473 1/20 0.32
CHRM1 P11229 1/20 0.32
PTGS2 P35354 2/20 0.32
PTGS1 P23219 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MAPT P10636 1/20 0.32
CYP1A2 P05177 1/20 0.31
NR1I2 O75469 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL82274 0.81 TAAR1 (0.40) TAAR1ALDH1A1CYP2A6CRHBPCRHR2
SCHEMBL3757997 0.74 CRHBP (0.36) TAAR1ALDH1A1CYP2A6CRHBPCRHR2
SCHEMBL29403344 0.73 CYP2A6 (0.36) TAAR1ALDH1A1CYP2A6CRHBPCRHR2
SCHEMBL356036 0.73 CYP2A6 (0.36) TAAR1ALDH1A1CYP2A6CRHBPCRHR2
SCHEMBL11268438 0.73 ALDH1A1 (0.43) ALDH1A1BACE1LMNANPSR1MAPT
SCHEMBL1877506 0.71 TAAR1 (0.40) TAAR1ALDH1A1HTTPTGS2NPSR1
SCHEMBL491126 0.71 CYP2A6 (0.41) ALDH1A1CYP2A6HSD11B1LMNATSHR
SCHEMBL491288 0.70 CYP1A2 (0.40) TAAR1ALDH1A1CRHBPCRHR2HTT
SCHEMBL17508555 0.70 CYP2A6 (0.39) TAAR1ALDH1A1CYP2A6CRHBPCRHR2
SCHEMBL490794 0.68 RELA (0.40) TAAR1ALDH1A1BACE1LMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921033-B2 Method of preparing lithographic printing plate and developer for lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2014-12-30 US disclosed
US-8921033-B2 Method of preparing lithographic printing plate and developer for lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2014-12-30 US disclosed
US-8846300-B2 Developer for processing lithographic printing plate precursor, method for manufacturing lithographic printing plate by using the developer, and printing method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
EP-2261033-B1 Method of preparing lithographic printing plate FUJIFILM CORP (JP) 2014-08-27 EP disclosed
US-20130014658-A1 DEVELOPER FOR PROCESSING LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING LITHOGRAPHIC PRINTING PLATE BY USING THE DEVELOPER, AND PRINTING METHOD FUJIFILM CORPORATION (JP) 2013-01-17 US disclosed
US-20120322009-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE AND DEVELOPER FOR LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2012-12-20 US disclosed
US-20120322009-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE AND DEVELOPER FOR LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2012-12-20 US disclosed
US-20110159437-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-06-30 US disclosed
US-20110159437-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-06-30 US disclosed