SCHEMBL17510071

SCHEMBL17510071

CCC(CCO)c1c[c]ccc1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.35
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2178249 0.85 LMNA (0.35) LMNA
SCHEMBL14895838 0.79 LMNA (0.37) TRPA1LMNA
SCHEMBL5562190 0.78 ESR1 (0.34)
SCHEMBL18793698 0.77 TRPA1 (0.50) TRPA1LMNA
SCHEMBL27710909 0.77 TRPA1 (0.50) TRPA1LMNA
SCHEMBL1144424 0.77 TRPA1 (0.50) TRPA1LMNA
SCHEMBL28074215 0.77 TRPA1 (0.31) TRPA1
SCHEMBL3814993 0.77 RIPK1 (0.35) TRPA1LMNA
SCHEMBL1420932 0.76 TAAR1 (0.31)
SCHEMBL7429290 0.76 LMNA (0.37) TRPA1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2791120-B1 1,3,5 -TRIAZINE-2-AMINE DERIVATIVES, PREPARATION THEREOF AND DIAGNOSTIC AND THERAPEUTIC USE THEREOF SANOFI SA (FR) 2016-02-24 EP claimed