Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17514012 | 0.83 | FFAR1 (0.37) | NPC1RAB9AL3MBTL1MAPTFFAR1 | |
| SCHEMBL17513888 | 0.83 | ALOX5 (0.44) | NPC1RAB9AL3MBTL1MAPTFFAR1 | |
| SCHEMBL17513901 | 0.80 | GPR52 (0.40) | NPC1RAB9AL3MBTL1MAPTCYP1A2 | |
| SCHEMBL18797878 | 0.79 | AOC3 (0.38) | NPC1RAB9AL3MBTL1KMT2ALMNA | |
| SCHEMBL17513880 | 0.77 | ALOX5 (0.43) | NPC1RAB9AL3MBTL1FFAR1SMN1; SMN2 | |
| SCHEMBL18797855 | 0.75 | ALOX5 (0.39) | L3MBTL1FFAR1TDP1KMT2ALMNA | |
| SCHEMBL17513925 | 0.74 | LMNA (0.48) | NPC1RAB9AL3MBTL1FFAR1SMN1; SMN2 | |
| SCHEMBL17513904 | 0.74 | GPR52 (0.43) | NPC1RAB9AL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL17513997 | 0.73 | GRM5 (0.41) | NPC1RAB9ASMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL17513938 | 0.73 | CA12 (0.39) | NPC1RAB9AL3MBTL1MAPTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197482-A1 | METHODS OF TREATING TRAUMATIC BRAIN INJURY | Oxeia Biopharmaceuticals Inc. (US) | 2017-08-02 | — | — | EP | disclosed |
| EP-3182992-A1 | METHODS OF TREATING MILD BRAIN INJURY | Oxeia Biopharmaceuticals Inc. (US) | 2017-06-28 | — | — | EP | disclosed |
| WO-2017075535-A1 | METHODS OF TREATING NEURODEGENERATIVE CONDITIONS | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2017-05-04 | — | — | WO | disclosed |
| WO-2016048488-A1 | METHODS OF TREATING TRAUMATIC BRAIN INJURY | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2016-03-31 | — | — | WO | disclosed |
| WO-2016028826-A1 | METHODS OF TREATING MILD BRAIN INJURY | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2016-02-25 | — | — | WO | disclosed |