SCHEMBL17515775

SCHEMBL17515775

O=S(=O)(O)c1ccccc1N=Nc1ccc(N=Nc2c(S(=O)(=O)O)cc3cc(Nc4ccccc4)ccc3c2O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.61
EP300 Q09472 1/20 0.61
PRMT6 Q96LA8 1/20 0.61
PRMT1 Q99873 1/20 0.61
CD40 P25942 1/20 0.60
CD40LG P29965 1/20 0.60
ENPP2 Q13822 10/20 0.59
PHLPP2 Q6ZVD8 2/20 0.58
FUT8 Q9BYC5 1/20 0.52
ALDH1A1 P00352 1/20 0.49
CYP1A2 P05177 1/20 0.49
HIF1A Q16665 1/20 0.49
MEN1 O00255 1/20 0.47
THRB P10828 1/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
TNNI3 P19429 1/20 0.46
TNNT2 P45379 1/20 0.46
TNNC1 P63316 1/20 0.46
HKDC1 Q2TB90 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17540343 0.92 PRMT1 (0.69) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL17515769 0.92 PRMT1 (0.69) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL17518451 0.90 CD40 (0.69) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL12757456 0.89 ENPP2 (0.69) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL17545808 0.89 ENPP2 (0.69) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL13350540 0.89 ENPP2 (0.69) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL29538227 0.89 ENPP2 (0.71) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL17540344 0.89 ENPP2 (0.67) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL17515771 0.89 ENPP2 (0.67) PRMT3EP300PRMT6PRMT1CD40
SCHEMBL20747587 0.88 PRMT1 (0.62) PRMT3EP300PRMT6PRMT1CD40

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190048194-A1 Azo Compound Or Salt Thereof, And Polarizing Film Containing Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-02-14 US disclosed
US-20170153361-A1 Achromatic Polarizing Plate With High-Transmissivity And High-Degree Of Polarization NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-06-01 US disclosed
US-20160041321-A1 Achromatic Dye-Based Highly-Transmissive Polarization Element, And Polarization Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-02-11 US disclosed