Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17517811 | 0.92 | ALDH1A1 (0.39) | HPGDHSD17B10CYP2D6CYP2C9ALOX15 | |
| SCHEMBL17430474 | 0.89 | KCNA5 (0.46) | HPGDHSD17B10TP53KDM4EALDH1A1 | |
| SCHEMBL29544302 | 0.89 | PTGS2 (0.46) | HPGDHSD17B10CYP2D6CYP2C9ALOX15 | |
| SCHEMBL15714991 | 0.85 | PTGS2 (0.43) | HPGDHSD17B10PTGS2TP53KDM4E | |
| SCHEMBL15714789 | 0.82 | MAPK1 (0.41) | PTGS2TP53KDM4EALDH1A1CYP3A4 | |
| SCHEMBL17432754 | 0.81 | ME2 (0.45) | HPGDHSD17B10PTGS1TP53KDM4E | |
| SCHEMBL17430479 | 0.79 | KCNA5 (0.45) | HPGDHSD17B10TP53KDM4EALDH1A1 | |
| SCHEMBL22170331 | 0.77 | PTGS2 (0.46) | HPGDALOX15PTGS2PTGS1KDM4E | |
| SCHEMBL10980169 | 0.76 | PTGS2 (0.53) | HPGDHSD17B10CYP2D6CYP2C9ALOX15 | |
| SCHEMBL15714814 | 0.75 | CYP19A1 (0.48) | HPGDHSD17B10CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9748487-B2 | Polymers based on naphthodiones | BASF SE (DE) | 2017-08-29 | — | — | US | disclosed |
| US-20160049588-A1 | POLYMERS BASED ON NAPHTHODIONES | BASF SE (DE) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160049588-A1 | POLYMERS BASED ON NAPHTHODIONES | CCND2, CCND1, PCNA | HPGD 1440/4885HSD17B10 2074/4885CYP2D6 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.