Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15714991 | 0.91 | PTGS2 (0.43) | PTGS2KMT2AHSP90AA1HSP90AB1PDE4B | |
| SCHEMBL29544302 | 0.89 | PTGS2 (0.46) | PTGS2KMT2AHSP90AA1HSP90AB1PDE4B | |
| SCHEMBL22170333 | 0.82 | PTGS2 (0.45) | PTGS2KMT2AHSP90AA1HSP90AB1FGFR1 | |
| SCHEMBL571569 | 0.81 | MEN1 (0.44) | PTGS2KMT2AHSP90AA1MAPTLMNA | |
| SCHEMBL592300 | 0.78 | PTGS2 (0.65) | PTGS2KMT2APDE4BFGFR1FGFR2 | |
| SCHEMBL17517796 | 0.77 | HPGD (0.40) | PTGS2KMT2AMAPTLMNAHTT | |
| SCHEMBL15714789 | 0.77 | MAPK1 (0.41) | PTGS2KMT2AHSP90AA1MAPTLMNA | |
| SCHEMBL10089222 | 0.76 | PTGS2 (0.47) | PTGS2KMT2AHSP90AA1HSP90AB1PDE4B | |
| SCHEMBL10736364 | 0.75 | PTGS2 (0.69) | PTGS2KMT2APDE4BMAPTLMNA | |
| SCHEMBL17432754 | 0.73 | ME2 (0.45) | FGFR1FGFR2FGFR4FGFR3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200208007-A1 | STIMULI-RESPONSIVE COLOR-CHANGING FUNCTIONAL COATING, PREPARATION METHOD AND APPLICATION THEREOF | UNIVERSITY OF AKRON | 2020-07-02 | — | — | US | disclosed |