SCHEMBL17430474

SCHEMBL17430474

COc1ccc(C2=c3ccc4c5c(ccc4c3OC2=O)=C(c2ccc(C)cc2)C(=O)O5)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 1/20 0.46
KCNH2 Q12809 1/20 0.46
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
MAOB P27338 4/20 0.44
ACHE P22303 1/20 0.43
ALKBH3 Q96Q83 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
EDNRA P25101 1/20 0.42
ME2 P23368 1/20 0.41
ME1 P48163 1/20 0.41
ME3 Q16798 1/20 0.41
ALOX5 P09917 1/20 0.40
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
CSNK2A1 P68400 1/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17432754 0.94 ME2 (0.45) KCNA5KCNH2MAOBNPC1RAB9A
SCHEMBL17517796 0.89 HPGD (0.40) KMT2AMEN1MAOBNPC1RAB9A
SCHEMBL17430479 0.89 KCNA5 (0.45) KCNA5KCNH2KMT2AMEN1MAOB
SCHEMBL17432765 0.83 MAPT (0.45) KCNA5KCNH2KMT2AMEN1NPC1
SCHEMBL17517811 0.82 ALDH1A1 (0.39) KMT2AMEN1MAOBNPC1RAB9A
SCHEMBL29544302 0.80 PTGS2 (0.46) KMT2AMEN1MAOBNPC1RAB9A
SCHEMBL17430475 0.79 ALKBH3 (0.47) KCNA5KCNH2KMT2AMEN1MAOB
SCHEMBL17430572 0.77 ACHE (0.54) KCNA5KCNH2KMT2AMEN1MAOB
SCHEMBL17430487 0.76 MAOB (0.45) KCNA5KCNH2KMT2AMEN1MAOB
SCHEMBL15714991 0.76 PTGS2 (0.43) KMT2AMEN1NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170062746-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING ELEMENT FUJIFILM CORPORATION (JP) 2017-03-02 US disclosed
US-20160013426-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING DEVICE, OPTICAL SENSOR, AND METHOD OF USING PHOTOELECTRIC CONVERSION ELEMENT FUJIFILM CORPORATION (JP) 2016-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160013426-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING DEVICE, OPTICAL SENSOR, AND METHOD OF USING PHOTOELECTRIC CONVERSION ELEMENT PPOX, PIN4, CRY1 KCNA5 835/4885KCNH2 493/4885KMT2A 3448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.