Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17518367 | 0.87 | MMP3 (0.35) | MMP3MMP9PSMB5MMP1 | |
| SCHEMBL17518250 | 0.82 | MMP3 (0.38) | MMP3MMP9PSMB5MMP1 | |
| SCHEMBL17518374 | 0.77 | — | — | |
| SCHEMBL17524643 | 0.75 | MMP3 (0.31) | MMP3MMP9MMP1 | |
| SCHEMBL17518275 | 0.75 | MMP3 (0.32) | MMP3MMP9PSMB5MMP1 | |
| SCHEMBL18377675 | 0.74 | PSMB5 (0.33) | MMP3MMP9PSMB5MMP1 | |
| SCHEMBL17087571 | 0.73 | MMP3 (0.32) | MMP3MMP9 | |
| SCHEMBL17524642 | 0.72 | MMP9 (0.32) | MMP3MMP9MMP1 | |
| SCHEMBL18123789 | 0.72 | MMP2 (0.31) | MMP9 | |
| SCHEMBL17518392 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039880-A1 | CYCLOSPORIN A ANALOGS | ALLERGAN, INC. | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039880-A1 | CYCLOSPORIN A ANALOGS | TSLP, CHP1, PPP3R1 | MMP3 4367/4885MMP9 4468/4885PSMB5 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.