Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1751585 | 0.72 | L3MBTL1 (0.42) | L3MBTL1KDM4EKMT2AMEN1TSHR | |
| SCHEMBL7928086 | 0.68 | HPGD (0.38) | L3MBTL1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL5010541 | 0.67 | ALDH1A1 (0.51) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL289801 | 0.67 | ALDH1A1 (0.43) | L3MBTL1KDM4EKMT2AMEN1TSHR | |
| SCHEMBL27721820 | 0.64 | L3MBTL1 (0.56) | L3MBTL1KDM4EKMT2AMEN1TSHR | |
| SCHEMBL3912497 | 0.63 | EPHX2 (0.45) | KDM4EMAPTLMNA | |
| SCHEMBL1580142 | 0.63 | L3MBTL1 (0.39) | L3MBTL1KDM4EKMT2AMEN1NPC1 | |
| SCHEMBL1751111 | 0.62 | L3MBTL1 (0.57) | L3MBTL1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL2219641 | 0.62 | FFAR1 (0.42) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL25247891 | 0.62 | CHRNB4 (0.45) | L3MBTL1KDM4EKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968590-B2 | IAP binding compounds | TETRALOGIC PHARMACEUTICALS CORPORATION (US) | 2011-06-28 | — | — | US | disclosed |