Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21046990 | 0.87 | HSP90AA1 (0.40) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL29683128 | 0.87 | HSP90AA1 (0.40) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL3394438 | 0.81 | LMNA (0.46) | BRD9LMNAPOLBRXFP1METAP1 | |
| SCHEMBL5776777 | 0.80 | METAP1 (0.49) | BRD9LMNAPOLBRXFP1METAP1 | |
| SCHEMBL1063858 | 0.80 | NAMPT (0.45) | MEN1KMT2AALDH1A1MAPTBRD9 | |
| SCHEMBL24110547 | 0.80 | LMNA (0.48) | BRD9LMNAPOLBRXFP1METAP1 | |
| SCHEMBL4774446 | 0.80 | PDK1 (0.57) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL30914163 | 0.80 | PDK1 (0.57) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL3053094 | 0.79 | ALDH1A1 (0.60) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL15912303 | 0.79 | KDM4E (0.60) | MEN1KMT2AKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11779568-B2 | Autotaxin inhibitor compounds | SABRE THERAPEUTICS LLC (US) | 2023-10-10 | — | — | US | disclosed |
| US-11779568-B2 | Autotaxin inhibitor compounds | SABRE THERAPEUTICS LLC (US) | 2023-10-10 | — | — | US | disclosed |
| US-11344533-B2 | Autotaxin inhibitor compounds | SABRE THERAPEUTICS LLC (US) | 2022-05-31 | — | — | US | disclosed |
| US-20200268713-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2020-08-27 | — | — | US | disclosed |
| US-10688081-B2 | Autotaxin inhibitor compounds | SABRE THERAPEUTICS LLC (US) | 2020-06-23 | — | — | US | disclosed |
| US-9999615-B2 | Autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2018-06-19 | — | — | US | disclosed |
| US-9999615-B2 | Autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2018-06-19 | — | — | US | disclosed |
| US-9714240-B2 | Vinyl autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-20160374991-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-12-29 | — | — | US | disclosed |
| US-9468628-B2 | Autotaxin inhibitor compounds | PHARMAKEA, INC (US) | 2016-10-18 | — | — | US | disclosed |
| US-20160235713-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-08-18 | — | — | US | disclosed |
| US-20160222000-A1 | VINYL AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-08-04 | — | — | US | disclosed |
| US-9334261-B2 | Autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2016-05-10 | — | — | US | disclosed |
| US-20160046614-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160374991-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINE1 | MEN1 737/4885KMT2A 2780/4885KDM4E 4044/4885 |
| US-11779568-B2 | Autotaxin inhibitor compounds | ENPP2, SERPINB1, SERPINE1 | MEN1 737/4885KMT2A 2780/4885KDM4E 4044/4885 |
| US-20160046614-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINE1 | MEN1 737/4885KMT2A 2780/4885KDM4E 4044/4885 |
| US-10688081-B2 | Autotaxin inhibitor compounds | ENPP2, SERPINB1, SERPINE1 | MEN1 737/4885KMT2A 2780/4885KDM4E 4044/4885 |
| US-11344533-B2 | Autotaxin inhibitor compounds | ENPP2, SERPINB1, SERPINE1 | MEN1 737/4885KMT2A 2780/4885KDM4E 4044/4885 |
| US-20200268713-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINE1 | MEN1 737/4885KMT2A 2780/4885KDM4E 4044/4885 |
| US-20160222000-A1 | VINYL AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINB10 | MEN1 910/4885KMT2A 1696/4885KDM4E 2416/4885 |
| US-20160235713-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINE1 | MEN1 737/4885KMT2A 2780/4885KDM4E 4044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.