Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17523391 | 1.00 | DPP4 (0.55) | DPP4LTA4HALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL17523390 | 1.00 | DPP4 (0.55) | DPP4LTA4HALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL17523396 | 1.00 | DPP4 (0.55) | DPP4LTA4HALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL10253262 | 0.98 | LTA4H (0.53) | DPP4LTA4HALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL498360 | 0.85 | MAPK1 (0.39) | DPP4LTA4HALDH1A1KDM4EMAPT | |
| SCHEMBL14379745 | 0.85 | MAPK1 (0.39) | DPP4LTA4HALDH1A1KDM4EMAPT | |
| SCHEMBL23611278 | 0.82 | DPP4 (0.65) | DPP4LTA4HALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL13707354 | 0.82 | DPP4 (0.65) | DPP4LTA4HALDH1A1KDM4EL3MBTL1 | |
| Alpha-Terthienyl SCHEMBL147274 | 0.82 | DPP4 (0.65) | DPP4LTA4HALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1105086 | 0.82 | DPP4 (0.65) | DPP4LTA4HALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10766915-B2 | Metal-based coordination complexes as photodynamic compounds and their use | MCFARLAND SHERRI ANN (CA) | 2020-09-08 | — | — | US | disclosed |
| US-9676806-B2 | Metal-based thiophene photodynamic compounds and their use | MCFARLAND SHERRI ANN (CA) | 2017-06-13 | — | — | US | disclosed |
| US-9676806-B2 | Metal-based thiophene photodynamic compounds and their use | MCFARLAND SHERRI ANN (CA) | 2017-06-13 | — | — | US | disclosed |
| US-20160229878-A1 | METAL-BASED THIOPHENE PHOTODYNAMIC COMPOUNDS AND THEIR USE | MCFARLAND SHERRI ANN (CA) | 2016-08-11 | — | — | US | disclosed |
| US-9345769-B2 | Metal-based thiophene photodynamic compounds and their use | MCFARLAND SHERRI ANN (CA) | 2016-05-24 | — | — | US | disclosed |
| US-20160039854-A1 | METAL-BASED COORDINATION COMPLEXES AS PHOTODYNAMIC COMPOUNDS AND THEIR USE | MCFARLAND SHERRI ANN (CA) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229878-A1 | METAL-BASED THIOPHENE PHOTODYNAMIC COMPOUNDS AND THEIR USE | TP53, PPOX, HMBS | DPP4 451/4885LTA4H 1463/4885ALDH1A1 373/4885 |
| US-20160039854-A1 | METAL-BASED COORDINATION COMPLEXES AS PHOTODYNAMIC COMPOUNDS AND THEIR USE | PIN1, PPIF, PPOX | DPP4 866/4885LTA4H 2765/4885ALDH1A1 2483/4885 |
| US-10766915-B2 | Metal-based coordination complexes as photodynamic compounds and their use | PIN1, PPIF, PPOX | DPP4 866/4885LTA4H 2765/4885ALDH1A1 2483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.