Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | MPO | P05164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 5/20 | 0.43 |
| ▸ | HTR1B | P28222 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525726 | 0.85 | GAA (0.66) | SLC6A4RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL17525734 | 0.85 | MPO (0.64) | SLC6A4MPOKMT2AHTR2AHTR1A | |
| SCHEMBL6948769 | 0.81 | HTR2A (0.67) | RAB9ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL2825796 | 0.81 | RAB9A (0.70) | RAB9ASMN1; SMN2GAAMPOMAPT | |
| SCHEMBL11283499 | 0.79 | GAA (0.69) | SLC6A4GAAMAPTMEN1KMT2A | |
| SCHEMBL26508375 | 0.79 | MPO (0.67) | SLC6A4MPOHTR1DHTR1BHTR2A | |
| SCHEMBL2823989 | 0.76 | TRPM8 (0.62) | SLC6A4MAPTMEN1KMT2AHTR1D | |
| SCHEMBL733677 | 0.75 | RAB9A (0.69) | RAB9ASMN1; SMN2GAAMPOMAPT | |
| SCHEMBL27502150 | 0.71 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3MPOMAPT | |
| SCHEMBL8396474 | 0.71 | HTR1D (0.66) | SLC6A4MPOMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2985282-A1 | GLUTARIMIDE DERIVATIVES, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHODS FOR PRODUCING GLUTARIMIDE DERIVATIVES | Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) | 2016-02-17 | — | — | EP | disclosed |