SCHEMBL17528641

SCHEMBL17528641

C=CC(=O)Nc1ccc(-c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 10/20 0.73
KIF11 P52732 1/20 0.50
F13A1 P00488 1/20 0.50
LMNA P02545 1/20 0.50
TGM1 P22735 1/20 0.50
TGM3 Q08188 1/20 0.50
NMT1 P30419 1/20 0.47
GSTO1 P78417 1/20 0.47
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
DDAH1 O94760 1/20 0.46
ALDH1A1 P00352 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
EGFR P00533 1/20 0.43
MMP1 P03956 1/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
TDP2 O95551 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL648950 0.85 TGM2 (1.00) TGM2F13A1LMNATGM1TGM3
SCHEMBL14179111 0.81 TGM2 (0.70) TGM2F13A1LMNATGM1TGM3
SCHEMBL8465028 0.80 TGM2 (0.89) TGM2F13A1LMNATGM1TGM3
SCHEMBL1262239 0.78 TGM2 (0.61) TGM2F13A1LMNATGM1TGM3
SCHEMBL1263116 0.77 NR4A1 (0.65) TGM2F13A1LMNATGM1TGM3
SCHEMBL20456504 0.76 THRA (0.61) TGM2F13A1LMNATGM1TGM3
SCHEMBL13854054 0.76 ALDH1A1 (0.48) TGM2LMNATHRATHRBALDH1A1
SCHEMBL439369 0.76 TGM2 (0.79) TGM2F13A1LMNATGM1TGM3
SCHEMBL17240364 0.75 TGM2 (0.57) TGM2F13A1LMNATGM1TGM3
SCHEMBL1383664 0.75 TGM2 (0.78) TGM2F13A1LMNATGM1TGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11754901-B2 Electrochromic device, wearable device, and method for driving electrochromic device RICOH COMPANY, LTD. (JP) 2023-09-12 US disclosed
US-11754901-B2 Electrochromic device, wearable device, and method for driving electrochromic device RICOH COMPANY, LTD. (JP) 2023-09-12 US disclosed
US-20220035216-A1 ELECTROCHROMIC ELEMENT, AND METHOD FOR DRIVING THE SAME RICOH COMPANY, LTD. (JP) 2022-02-03 US disclosed
US-11209713-B2 Electrochromic element and electrochromic dimming element RICOH COMPANY, LTD. (JP) 2021-12-28 US disclosed
US-20210032531-A1 ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2021-02-04 US disclosed
US-20200301226-A1 ELECTROCHROMIC DEVICE, WEARABLE DEVICE, AND METHOD FOR DRIVING ELECTROCHROMIC DEVICE RICOH COMPANY, LTD. (JP) 2020-09-24 US disclosed
US-10634970-B2 Electrochromic element RICOH COMPANY, LTD. (JP) 2020-04-28 US disclosed
US-20200103718-A1 ELECTROCHROMIC DISPLAY DEVICE AND PRODUCTION METHOD OF ELECTROCHROMIC DISPLAY DEVICE RICOH COMPANY, LTD. (JP) 2020-04-02 US disclosed
EP-3177963-B1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH CO LTD (JP) 2020-02-19 EP disclosed
US-10429710-B2 Electrochromic device RICOH COMPANY, LTD. (JP) 2019-10-01 US disclosed
US-20190285960-A1 ELECTROCHROMIC DEVICE, ELECTRONIC DIMMING EYEGLASSES, AUGMENTED REALITY EYEGLASSES, AND CAMERA RICOH COMPANY, LTD. (JP) 2019-09-19 US disclosed
US-10409129-B2 Electrochromic element RICOH COMPANY, LTD. (JP) 2019-09-10 US disclosed
US-20170329199-A1 ELECTROCHROMIC DEVICE RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170329199-A1 ELECTROCHROMIC DEVICE RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170329198-A1 ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170329198-A1 ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2017-08-17 US disclosed
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2017-08-17 US disclosed
WO-2016021129-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2016-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210032531-A1 ELECTROCHROMIC ELEMENT TMEM109, DSG1, GPX1 TGM2 1156/4885KIF11 1476/4885F13A1 1596/4885
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT TET2, TET1, TET3 TGM2 1268/4885KIF11 2422/4885F13A1 3994/4885
US-11209713-B2 Electrochromic element and electrochromic dimming element TET2, TET1, TET3 TGM2 1268/4885KIF11 2422/4885F13A1 3994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.