Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.55 |
| ▸ | MPL | P40238 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.37 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.37 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925499 | 0.71 | KCNMA1 (1.00) | KCNMA1MPLALDH1A1HPGDKDM4E | |
| SCHEMBL2925491 | 0.70 | KCNMA1 (0.68) | KCNMA1MPLALDH1A1HPGDKDM4E | |
| SCHEMBL2931271 | 0.68 | KCNMA1 (0.50) | KCNMA1KDM4EMEN1KMT2AKIF11 | |
| SCHEMBL1818435 | 0.67 | KDM4E (0.62) | KCNMA1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL78221 | 0.67 | MRGPRX4 (0.61) | KCNMA1ALDH1A1HPGDKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL18861026 | 0.66 | MRGPRX4 (0.59) | KCNMA1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL6553697 | 0.66 | KDM4E (0.61) | KCNMA1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL8617573 | 0.66 | KDM4E (0.61) | KCNMA1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL1465827 | 0.65 | ALDH1A1 (0.68) | MPLALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21563889 | 0.64 | KDM4E (0.57) | KDM4EHSD17B10MEN1KMT2AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11517556-B2 | Composition for BKCa channel activation | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2022-12-06 | — | — | US | disclosed |
| US-20200069640-A1 | COMPOSITION FOR BKCA CHANNEL ACTIVATION | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-03-05 | — | — | US | disclosed |
| US-20190083456-A1 | COMPOSITION FOR BKCA CHANNEL ACTIVATION | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2019-03-21 | — | — | US | disclosed |
| US-20160061816-A1 | SCREENING METHOD FOR ION CHANNEL MODULATORS USING MUTATED BKCA CHANNEL | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069640-A1 | COMPOSITION FOR BKCA CHANNEL ACTIVATION | KCNAB1, KCNN3, KCNC1 | KCNMA1 8/4885MPL 4603/4885ALDH1A1 3836/4885 |
| US-11517556-B2 | Composition for BKCa channel activation | KCNAB1, KCNN3, KCNC1 | KCNMA1 8/4885MPL 4603/4885ALDH1A1 3836/4885 |
| US-20190083456-A1 | COMPOSITION FOR BKCA CHANNEL ACTIVATION | KCNAB1, KCNN3, KCNC1 | KCNMA1 8/4885MPL 4603/4885ALDH1A1 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.