Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Indole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.53 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.53 |
| ▸ | ITGAL | P20701 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | ADK | P55263 | 1/20 | 0.53 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.42 |
| ▸ | WNT3A | P56704 | 5/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indole SCHEMBL28215560 | 1.00 | TRPA1 (0.53) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL30530600 | 1.00 | TRPA1 (0.53) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL28021734 | 0.97 | TRPA1 (0.53) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL28113892 | 0.85 | TRPA1 (0.59) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL412813 | 0.84 | TRPA1 (0.57) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL14576775 | 0.83 | TRPA1 (0.65) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL30285645 | 0.83 | CA1 (0.71) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL17536616 | 0.83 | TRPA1 (0.55) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL17536619 | 0.83 | TRPA1 (0.55) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL28154294 | 0.83 | TRPA1 (0.55) | TRPA1CA1CA2ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113142058-B | Cutting propagation method for viburnum sargentii | 菁蕙集团有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-115160068-A | Special seedling raising agent for mechanized rice seedling raising and transplanting, and preparation method and application thereof | 张余 | 2022-10-11 | — | — | CN | claimed |
| CN-114365668-A | Planting method for green nursery stock | 昌邑市欣欣苗木种植专业合作社 | 2022-04-19 | — | — | CN | claimed |
| CN-113980164-A | Preparation method of super absorbent resin containing plant growth promoter | 潍坊科技学院 | 2022-01-28 | — | — | CN | claimed |
| CN-113229015-A | Rubber cultivation management method | 海南热作高科技研究院股份公司 | 2021-08-10 | — | — | CN | claimed |
| CN-112608180-A | Special rapid rooting agent for preparing industrial hemp | 黑龙江汉美生工业大麻科技有限公司 | 2021-04-06 | — | — | CN | claimed |
| CN-109380069-B | Tomato planting method | 武汉楚为生物科技股份有限公司 | 2020-12-22 | — | — | CN | claimed |
| CN-111587734-A | Non-test tube cloning method for aquilaria kirilowii seedlings | 广州市司农农业科技有限公司 | 2020-08-28 | — | — | CN | claimed |
| CN-107162727-A | The preparation of one planting fruit-trees special bacteria agent and application process | 江苏沃纳生物科技有限公司 | 2017-09-15 | — | — | CN | claimed |
| CN-106212186-A | A kind of implantation methods of willow 107 | 李宗顺 | 2016-12-14 | — | — | CN | claimed |
| WO-2025098145-A1 | ROOT PROMOTING AGENT FOR PROMOTING ROOTING OF CYCLOCARYA PALIURUS SOFTWOOD CUTTINGS, AND SEEDLING RAISING METHOD | 南京林业大学 | 2025-05-15 | — | — | WO | disclosed |
| CN-117617010-A | Method for breeding popcorn seedlings | 云南省农业科学院花卉研究所 | 2024-03-01 | — | — | CN | disclosed |
| CN-117617010-A | Method for breeding popcorn seedlings | 云南省农业科学院花卉研究所 | 2024-03-01 | — | — | CN | disclosed |
| CN-116584380-A | Tissue culture method suitable for Liupu tea mountain-sill purple stock seedlings | 河池学院 | 2023-08-15 | — | — | CN | disclosed |
| CN-113229015-B | Rubber cultivation management method | 海南热作高科技研究院有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-103183567-A | Liquid bacterial agent for rooting | ZHANG YUANBAO | 2013-07-03 | — | — | CN | disclosed |
| CN-102173912-B | Preparation method of hole fertilizer | SHANDONG LUHONG AGRICULTURE TECHNOLOGY CO LTD | 2012-05-09 | — | — | CN | disclosed |
| CN-102302036-A | high-efficiency seed soaking agent for sugarcanes and preparation method thereof | SOUTH SUBTROPICAL CROPS RES INST CATAS | 2012-01-04 | — | — | CN | disclosed |
| CN-102173912-A | Preparation method of cave-applied fertilizer | SHANDONG LUHONG AGRICULTURE TECHNOLOGY CO LTD | 2011-09-07 | — | — | CN | disclosed |
| CN-101823914-A | Method for preparing quick-acting synergist for fertilizer | SANZHONG HE | 2010-09-08 | — | — | CN | disclosed |