SCHEMBL17550610

SCHEMBL17550610

Cc1ccc2c([C@@H](C)N(C(=O)[C@H]3CNCCO3)C3CC3)nn(CCCNC(=O)O)c2n1

nearest known ligand 0.88

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15418065 1.00 REN (0.88) REN
SCHEMBL20548988 1.00 REN (0.88) REN
SCHEMBL19512220 1.00 REN (0.88) REN
SCHEMBL24294897 0.94 REN (0.84) REN
Sitokiren SCHEMBL29492575 0.94 REN (1.00) REN
Sitokiren SCHEMBL26960855 0.94 REN (1.00) REN
Sitokiren SCHEMBL19512224 0.94 REN (1.00) REN
Sitokiren SCHEMBL19512247 0.94 REN (1.00) REN
Sitokiren SCHEMBL16471588 0.94 REN (1.00) REN
Sitokiren SCHEMBL16471589 0.94 REN (1.00) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398946-B1 SALT OF MORPHOLINE DERIVATIVE AND CRYSTALLINE FORM THEREOF, AS WELL AS PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE OF THE SAME SHANGHAI PHARMACEUTICALS HOLDING CO LTD (CN) 2022-05-04 — — EP claimed
EP-2687518-B1 NITROGEN-CONTAINING SATURATED HETEROCYCLIC COMPOUND MITSUBISHI TANABE PHARMA CORP (JP) 2017-11-01 — — EP claimed
US-9278944-B2 Nitrogen-containing saturated heterocyclic compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2016-03-08 — — US claimed
EP-3398946-B1 SALT OF MORPHOLINE DERIVATIVE AND CRYSTALLINE FORM THEREOF, AS WELL AS PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE OF THE SAME SHANGHAI PHARMACEUTICALS HOLDING CO LTD (CN) 2022-05-04 — — EP disclosed
US-10519150-B2 Salts of morpholine derivative, crystal forms thereof, processes for producing the same, pharmaceutical compositions including the same, and use thereof SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) 2019-12-31 — — US disclosed
US-20190016718-A1 SALTS OF MORPHOLINE DERIVATIVE, CRYSTAL FORMS THEREOF, PROCESSES FOR PRODUCING THE SAME, PHARMACEUTICAL COMPOSITIONS INCLUDING THE SAME, AND USE THEREOF SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) 2019-01-17 — — US disclosed
EP-3398946-A1 SALT OF MORPHOLINE DERIVATIVE AND CRYSTALLINE FORM THEREOF, AS WELL AS PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE OF THE SAME Shanghai Pharmaceuticals Holding Co., Ltd. (CN) 2018-11-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10519150-B2 Salts of morpholine derivative, crystal forms thereof, processes for producing the same, pharmaceutical compositions including the same, and use thereof MDH1, MDH2, ME1 REN 171/4885
US-20190016718-A1 SALTS OF MORPHOLINE DERIVATIVE, CRYSTAL FORMS THEREOF, PROCESSES FOR PRODUCING THE SAME, PHARMACEUTICAL COMPOSITIONS INCLUDING THE SAME, AND USE THEREOF MDH1, MDH2, ME1 REN 171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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