Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RGS4 | P49798 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RGS8 | P57771 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1074421 | 0.83 | L3MBTL1 (0.46) | TDP1L3MBTL1RGS4ALDH1A1RGS8 | |
| SCHEMBL1729815 | 0.81 | HTT (0.42) | L3MBTL1MAPTALDH1A1GSK3BPDE4A | |
| SCHEMBL175121 | 0.76 | GSK3A (0.38) | TDP1L3MBTL1RGS4KDM4EALDH1A1 | |
| SCHEMBL17108478 | 0.74 | GSK3A (0.31) | GSK3B | |
| SCHEMBL1074044 | 0.67 | GSK3B (0.39) | L3MBTL1GSK3BPDE4BADORA2BLMNA | |
| SCHEMBL11637084 | 0.65 | MAPT (0.53) | MAPTATMRGS4KDM4EGAA | |
| SCHEMBL8777494 | 0.65 | TDP1 (0.68) | TDP1L3MBTL1RGS4GAAALDH1A1 | |
| SCHEMBL2784423 | 0.65 | ATM (0.53) | TDP1L3MBTL1MAPTATMRGS4 | |
| SCHEMBL1729644 | 0.64 | ADORA2B (0.40) | L3MBTL1MAPTATMKDM4EGAA | |
| SCHEMBL1729797 | 0.64 | FABP4 (0.44) | MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611814-A1 | METHOD FOR PRODUCING DITHIIN-TETRACARBOXIMIDES | Bayer Intellectual Property GmbH (DE) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012028588-A1 | METHOD FOR PRODUCING DITHIIN-TETRACARBOXIMIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |