SCHEMBL1074044

SCHEMBL1074044

CCn1c(=O)c2sc3c(=O)n(CC)c(=O)c3sc2c1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 5/20 0.39
GSK3A P49840 4/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
PDE7A Q13946 7/20 0.36
KMT2A Q03164 2/20 0.35
ADORA2B P29275 1/20 0.35
F2 P00734 1/20 0.35
ELANE P08246 1/20 0.35
CTSG P08311 1/20 0.35
CTRC Q99895 1/20 0.35
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
PDE4B Q07343 2/20 0.34
PDE7B Q9NP56 1/20 0.34
GRIA1 P42261 1/20 0.33
GRIA2 P42262 1/20 0.33
GRIA3 P42263 1/20 0.33
GRIA4 P48058 1/20 0.33
KAT2B Q92831 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1729815 0.87 HTT (0.42) GSK3BGSK3AL3MBTL1PDE7AKMT2A
SCHEMBL28475407 0.78
SCHEMBL4307720 0.78 GSK3B (0.39) GSK3BGSK3AADORA2BF2ELANE
Hydrochloric Acid SCHEMBL27848734 0.76
SCHEMBL1729644 0.75 ADORA2B (0.40) L3MBTL1KMT2AADORA2BHPGDHTT
SCHEMBL1074421 0.74 L3MBTL1 (0.46) GSK3BL3MBTL1ADORA2BHPGDKAT2B
SCHEMBL1746830 0.69 ALDH1A1 (0.36) KMT2APDE4BMEN1LMNA
SCHEMBL15984262 0.68 SRC (0.39) KMT2AHPGDHTTMAPK1NPSR1
SCHEMBL8316287 0.67 GSK3B (0.32) GSK3BGSK3AADORA2BNPSR1
SCHEMBL174588 0.67 GSK3A (0.40) GSK3BGSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160024108-A1 USE OF DITHIINE-TETRACARBOXIMIDES FOR CONTROLLING BACTERIAL HARMFUL ORGANISMS IN USEFUL PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-01-28 US claimed
EP-2967068-A1 USE OF DITHIINE-TETRACARBOXIMIDES FOR CONTROLLING BACTERIAL HARMFUL ORGANISMS IN USEFUL PLANTS Bayer CropScience Aktiengesellschaft (DE) 2016-01-20 EP claimed
WO-2014139897-A1 USE OF DITHIINE-TETRACARBOXIMIDES FOR CONTROLLING BACTERIAL HARMFUL ORGANISMS IN USEFUL PLANTS BAYER CROPSCIENCE AG (DE) 2014-09-18 WO claimed
US-20130316901-A1 SYNERGISTIC COMBINATIONS CONTAINING A DITHINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-11-28 US claimed
EP-2386203-B1 Use of dithiin tetracarboximides for combating phytopathogenic fungi BAYER CROPSCIENCE AG (DE) 2013-11-20 EP claimed
EP-2454939-A1 Post-harvest treatment Bayer CropScience AG (DE) 2012-05-23 EP claimed
US-20110280958-A1 Active Compound Combinations BAYER CROPSCIENCE AG (DE) 2011-11-17 US claimed
EP-2386203-A2 Use of dithiin tetracarboximides for combating phytopathogenic fungi Bayer CropScience AG (DE) 2011-11-16 EP claimed
US-8040455-B2 Display device and information processing device having the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-10-18 US claimed
US-20160286810-A1 ACTIVE COMPOUND COMBINATIONS BAYER CROPSCIENCE AG (DE) 2016-10-06 US disclosed
US-20160024108-A1 USE OF DITHIINE-TETRACARBOXIMIDES FOR CONTROLLING BACTERIAL HARMFUL ORGANISMS IN USEFUL PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-01-28 US disclosed
EP-2967068-A1 USE OF DITHIINE-TETRACARBOXIMIDES FOR CONTROLLING BACTERIAL HARMFUL ORGANISMS IN USEFUL PLANTS Bayer CropScience Aktiengesellschaft (DE) 2016-01-20 EP disclosed
US-9192161-B2 Fungicidal combinations comprising a dithiino-tetracarboxamide fungicide BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-11-24 US disclosed
US-9155307-B2 Active compound combinations BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-10-13 US disclosed
US-8040455-B2 Display device and information processing device having the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-10-18 US disclosed
WO-2011061156-A1 ACTIVE COMPOUND COMBINATIONS BAYER CROPSCIENCE AG (DE) 2011-05-26 WO disclosed
US-20110118115-A1 Active compound combinations BAYER CROPSCIENCE AG (DE) 2011-05-19 US disclosed
EP-2271219-A1 USE OF DITHIIN TETRACARBOXIMIDES FOR TREATING PHYTOPATHOGENIC FUNGI Bayer CropScience AG (DE) 2011-01-12 EP disclosed
US-20100120884-A1 USE OF DITHIINE-TETRACARBOXIMIDES FOR CONTROLLING PHYTOPATHOGENIC FUNGI BAYER CROPSCIENCE AG (DE) 2010-05-13 US disclosed
WO-2010043319-A1 USE OF DITHIIN TETRACARBOXIMIDES FOR TREATING PHYTOPATHOGENIC FUNGI BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118115-A1 Active compound combinations AADAC, ACACA, DDT GSK3B 1496/4885GSK3A 1921/4885L3MBTL1 2163/4885
US-20160286810-A1 ACTIVE COMPOUND COMBINATIONS TST, DPM1, BROX GSK3B 838/4885GSK3A 1182/4885L3MBTL1 3335/4885
US-20130316901-A1 SYNERGISTIC COMBINATIONS CONTAINING A DITHINO-TETRACARBOXAMIDE FUNGICIDE AND A HERBICIDE, SAFENER OR PLANT GROWTH REGULATOR DDT, ING2, DNER GSK3B 2076/4885GSK3A 2074/4885L3MBTL1 2552/4885
US-20100120884-A1 USE OF DITHIINE-TETRACARBOXIMIDES FOR CONTROLLING PHYTOPATHOGENIC FUNGI TST, TTI1, DPM1 GSK3B 3299/4885GSK3A 3513/4885L3MBTL1 1451/4885
US-20110280958-A1 Active Compound Combinations TST, QDPR, SQOR GSK3B 708/4885GSK3A 987/4885L3MBTL1 4089/4885
US-20160024108-A1 USE OF DITHIINE-TETRACARBOXIMIDES FOR CONTROLLING BACTERIAL HARMFUL ORGANISMS IN USEFUL PLANTS MGAM, PGLS, DGKI GSK3B 2909/4885GSK3A 2133/4885L3MBTL1 753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.