Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2679583 | 0.84 | ELANE (0.47) | MMP1MMP2MMP9MMP12NPC1 | |
| SCHEMBL1756467 | 0.84 | RAB9A (0.44) | MMP1MMP2MMP9MMP12NPC1 | |
| SCHEMBL1756479 | 0.84 | RAB9A (0.44) | MMP1MMP2MMP9MMP12NPC1 | |
| SCHEMBL525049 | 0.80 | MMP1 (0.45) | MMP1MMP2MMP9MMP12NPC1 | |
| SCHEMBL3421330 | 0.79 | RAB9A (0.42) | MMP1MMP2MMP9MMP12NPC1 | |
| SCHEMBL27588298 | 0.79 | MMP1 (0.40) | MMP1MMP2MMP9MMP12NPC1 | |
| Hydrochloric Acid SCHEMBL27610314 | 0.78 | MMP1 (0.44) | MMP1MMP2MMP9MMP12NPC1 | |
| SCHEMBL27711054 | 0.78 | MMP1 (0.41) | MMP1MMP2MMP9MMP12NPC1 | |
| SCHEMBL27603109 | 0.77 | TRPM8 (0.47) | MMP1MMP2MMP9MMP12NPC1 | |
| SCHEMBL8327418 | 0.77 | KMT2A (0.47) | MMP1MMP2MMP9MMP12NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1591531-B1 | PROCESS FOR ACYL-TRANSFER ENZYME REACTIONS WITH ACYL- COENZYME A | SHOWA DENKO KK (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-7943351-B2 | Method for acyltransferase reaction using acyl coenzyme A | SHOWA DENKO K.K. (JP) | 2011-05-17 | — | — | US | disclosed |
| US-20090111153-A1 | METHOD FOR ACYLTRANSFERASE REACTION USING ACYL COENZYME A | SHOWA DENKO K.K. | 2009-04-30 | — | — | US | disclosed |
| US-7476521-B2 | acyl group of acyl coenzyme A is transferred to an acyl group receptor characterized in that the reaction is carried out by production and/or reproduction of acyl coenzyme A from coenzyme A in a reaction system by a chemical thioester exchange reaction with acylthioester | SHOWA DENKO K.K. (JP) | 2009-01-13 | — | — | US | disclosed |
| US-20060148048-A1 | acyl group of acyl coenzyme A is transferred to an acyl group receptor characterized in that the reaction is carried out by production and/or reproduction of acyl coenzyme A from coenzyme A in a reaction system by a chemical thioester exchange reaction with acylthioester | SHOWA DENKO K.K. (JP) | 2006-07-06 | — | — | US | disclosed |
| EP-1591531-A1 | PROCESS FOR ACYL-TRANSFER ENZYME REACTIONS WITH ACYL- COENZYME A | Showa Denko K.K. (JP) | 2005-11-02 | — | — | EP | disclosed |