Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27622460 | 0.85 | ALDH1A1 (0.40) | ELANERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1756472 | 0.84 | MMP1 (0.39) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1756479 | 0.84 | RAB9A (0.44) | ELANERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1756467 | 0.84 | RAB9A (0.44) | ELANERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3421330 | 0.83 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL525049 | 0.80 | MMP1 (0.45) | ELANERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6715200 | 0.79 | BCHE (0.42) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL27610314 | 0.78 | MMP1 (0.44) | ELANERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27852212 | 0.78 | MMP1 (0.41) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8327418 | 0.77 | KMT2A (0.47) | RAB9ANPC1SMN1; SMN2ALDH1A1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457898-A1 | FULLERENE DERIVATIVE | Sumitomo Chemical Company Limited (JP) | 2012-05-30 | — | — | EP | disclosed |
| US-20120111411-A1 | FULLERENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120111411-A1 | FULLERENE DERIVATIVE | HCN2, KCNN2, TMEM109 | ELANE 2778/4885RAB9A 2284/4885NPC1 769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.