Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 8/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411356 | 0.81 | SMN1; SMN2 (0.44) | CTSLCTSSSMN1; SMN2 | |
| SCHEMBL4542544 | 0.80 | SMN1; SMN2 (0.54) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL17368071 | 0.79 | SIRT2 (0.60) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL8773812 | 0.78 | SMN1; SMN2 (0.44) | CTSLCTSSSMN1; SMN2 | |
| SCHEMBL20966571 | 0.77 | GPR84 (0.51) | SIRT2SIRT1 | |
| SCHEMBL31674543 | 0.77 | GPR84 (0.51) | SIRT2SIRT1 | |
| SCHEMBL6370981 | 0.77 | GPR84 (0.51) | SIRT2SIRT1 | |
| SCHEMBL22033713 | 0.77 | GPR84 (0.51) | SIRT2SIRT1 | |
| SCHEMBL15710472 | 0.77 | GPR84 (0.51) | SIRT2SIRT1 | |
| SCHEMBL5973119 | 0.77 | CTSL (0.58) | SIRT2SIRT1SIRT3CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160311762-A1 | HYDRAZINYL LIPIDOIDS AND USES THEREOF | Preceres Inc. (US) | 2016-10-27 | — | — | US | disclosed |
| US-9409869-B1 | Hydrazinyl lipidoids and uses thereof | Preceres Inc. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20160221960-A1 | Hydrazinyl Lipidoids and Uses Thereof | Preceres Inc. (US) | 2016-08-04 | — | — | US | disclosed |
| US-9363992-B2 | Hydrazinyl lipidoids and uses thereof | Preceres Inc. (US) | 2016-06-14 | — | — | US | disclosed |
| US-9339029-B2 | Hydrazinyl lipidoids and uses thereof | Preceres Inc. (US) | 2016-05-17 | — | — | US | disclosed |
| US-20160073629-A1 | Hydrazinyl Lipidoids and Uses Thereof | Preceres Inc. (US) | 2016-03-17 | — | — | US | disclosed |
| US-20160066569-A1 | Hydrazinyl Lipidoids and Uses Thereof | Preceres Inc. (US) | 2016-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160066569-A1 | Hydrazinyl Lipidoids and Uses Thereof | LIPA, ABCB4, NPC1L1 | SIRT2 692/4885SIRT1 1174/4885SIRT3 1208/4885 |
| US-20160073629-A1 | Hydrazinyl Lipidoids and Uses Thereof | LIPA, ABCB4, NPC1L1 | SIRT2 692/4885SIRT1 1174/4885SIRT3 1208/4885 |
| US-20160221960-A1 | Hydrazinyl Lipidoids and Uses Thereof | LIPA, ABCB4, NPC1L1 | SIRT2 692/4885SIRT1 1174/4885SIRT3 1208/4885 |
| US-20160311762-A1 | HYDRAZINYL LIPIDOIDS AND USES THEREOF | LIPA, ABCB4, NPC1L1 | SIRT2 692/4885SIRT1 1174/4885SIRT3 1208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.