Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266456 | 0.81 | CES2 (0.50) | CES2CES1NR4A1NR4A2NR4A3 | |
| SCHEMBL4022029 | 0.81 | CES2 (0.50) | CES2CES1NR4A1NR4A2NR4A3 | |
| SCHEMBL28127817 | 0.79 | CES2 (0.48) | CES2CES1NR4A1NR4A2NR4A3 | |
| SCHEMBL2056188 | 0.76 | CES2 (0.45) | CES2CES1NR4A1NR4A2NR4A3 | |
| SCHEMBL6816545 | 0.76 | CES2 (0.45) | CES2CES1NR4A1NR4A2NR4A3 | |
| SCHEMBL8309008 | 0.76 | KIF11 (0.50) | CES2CES1NR4A1NR4A2NR4A3 | |
| SCHEMBL18242237 | 0.75 | CES2 (0.58) | CES2CES1NR4A1NR4A2NR4A3 | |
| SCHEMBL23131159 | 0.75 | NR4A1 (0.46) | CES2CES1NR4A1NR4A2NR4A3 | |
| SCHEMBL13819189 | 0.73 | HTR3E (0.47) | CES2CES1NR4A1NR4A2NR4A3 | |
| SCHEMBL17574202 | 0.72 | MTOR (0.53) | MTORALDH1A1LMNARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016033635-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2016-03-10 | — | — | WO | disclosed |