Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022029 | 1.00 | CES2 (0.50) | CES2CES1NR4A1NR4A2NR4A3 | |
| SCHEMBL8309008 | 0.94 | KIF11 (0.50) | CES2CES1NR4A1NR4A2NR4A3 | |
| Trifluoromethylbenzene SCHEMBL28068069 | 0.86 | ALDH1A1 (0.54) | CES2NR4A1NR4A2NR4A3CA9 | |
| SCHEMBL17574261 | 0.81 | CES2 (0.48) | CES2CES1NR4A1NR4A2NR4A3 | |
| SCHEMBL28127817 | 0.81 | CES2 (0.48) | CES2CES1NR4A1NR4A2NR4A3 | |
| SCHEMBL12360950 | 0.81 | CA9 (0.52) | CA9ALDH1A1LMNARAB9A | |
| SCHEMBL14298196 | 0.81 | CA9 (0.52) | CA9ALDH1A1LMNARAB9A | |
| SCHEMBL11620296 | 0.80 | CA9 (0.44) | NR4A1NR4A2NR4A3CA9ALDH1A1 | |
| SCHEMBL4833231 | 0.80 | CA9 (0.55) | SRD5A2CA9ALDH1A1LMNARAB9A | |
| SCHEMBL4833241 | 0.80 | CA9 (0.55) | SRD5A2CA9ALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574135-B | 4-aryl-5-thioether-2-difluoromethyl oxazole, and derivatives and synthesis method thereof | 湖南工程学院 | 2022-09-23 | — | — | CN | claimed |
| CN-110669070-B | Synthesis method of O- (dialkyl phosphinic group) ketoxime | 成都理工大学 | 2021-08-27 | — | — | CN | claimed |
| CN-112574135-A | 4-aryl-5-thioether-2-difluoromethyl oxazole, and derivatives and synthesis method thereof | 湖南工程学院 | 2021-03-30 | — | — | CN | claimed |
| CN-110669070-A | Synthesis method of O- (dialkyl phosphinic group) ketoxime | 成都理工大学 | 2020-01-10 | — | — | CN | claimed |
| US-11834420-B2 | Preparation method of pyrimidinylthio-benzoate oxime ester compound and application thereof as herbicide | Changzhou University (CN) | 2023-12-05 | — | — | US | disclosed |
| CN-113735773-B | 2, 3-dihydro-1, 2-diazacyclobutene oxynitride and preparation method thereof | 成都大学 | 2023-05-19 | — | — | CN | disclosed |
| CN-110642748-B | O- (2-trifluoromethyl-2-hydroxyethyl) oxime ether derivative and synthetic method and application thereof | 华南理工大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-112574135-B | 4-aryl-5-thioether-2-difluoromethyl oxazole, and derivatives and synthesis method thereof | 湖南工程学院 | 2022-09-23 | — | — | CN | disclosed |
| CN-110317177-B | Preparation method of pyrimidine salicylic acid oxime ester compound and application of pyrimidine salicylic acid oxime ester compound as herbicide | 常州大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-109651191-B | Difluoromethyl oxime ether derivative and synthetic method thereof | 华南理工大学 | 2021-11-19 | — | — | CN | disclosed |
| CN-110669070-B | Synthesis method of O- (dialkyl phosphinic group) ketoxime | 成都理工大学 | 2021-08-27 | — | — | CN | disclosed |
| US-20210221773-A1 | Preparation Method of Pyrimidinylthio-benzoate Oxime Ester Compound and Application thereof as Herbicide | Changzhou University (CN) | 2021-07-22 | — | — | US | disclosed |
| US-20050113576-A1 | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor | ABBOTT LABORATORIES | 2005-05-26 | — | — | US | disclosed |
| EP-1478363-A1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | Abbott Laboratories (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20040209884-A1 | Fused azabicycic compounds that inhibit vanilloid receptor subtype 1(VR1) receptor | ABBVIE INC. | 2004-10-21 | — | — | US | disclosed |
| US-20040157849-A1 | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor | ABBVIE INC. | 2004-08-12 | — | — | US | disclosed |
| WO-2003070247-A1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | ABBOTT LABORATORIES (US) | 2003-08-28 | — | — | WO | disclosed |
| US-20030158198-A1 | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor | ABBVIE INC. | 2003-08-21 | — | — | US | disclosed |
| EP-0658547-B1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEM CORP (JP) | 1998-03-11 | — | — | EP | disclosed |
| EP-0658547-A1 | N-pyrazolyl carbamate derivative, agricultural/horticultural fungicide containing the same as active ingredient and production intermediate thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158198-A1 | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor | TRPV1, VIPR1, TMEM109 | CES2 3942/4885CES1 1711/4885NR4A1 146/4885 |
| US-20040157849-A1 | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor | TRPV1, VIPR1, TMEM109 | CES2 3712/4885CES1 1557/4885NR4A1 155/4885 |
| US-11834420-B2 | Preparation method of pyrimidinylthio-benzoate oxime ester compound and application thereof as herbicide | ADH1C, ADH1A, AQP4 | CES2 1236/4885CES1 1752/4885NR4A1 3372/4885 |
| US-20040209884-A1 | Fused azabicycic compounds that inhibit vanilloid receptor subtype 1(VR1) receptor | TRPV1, TMEM109, GPR55 | CES2 3709/4885CES1 1763/4885NR4A1 138/4885 |
| US-20050113576-A1 | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor | TRPV1, TMEM109, VIPR1 | CES2 3701/4885CES1 1819/4885NR4A1 160/4885 |
| US-20210221773-A1 | Preparation Method of Pyrimidinylthio-benzoate Oxime Ester Compound and Application thereof as Herbicide | ADH1C, ADH1A, AQP4 | CES2 1210/4885CES1 1867/4885NR4A1 3412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.