Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | TOP1 | P11387 | 2/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | DBH | P09172 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758192 | 0.87 | CA12 (0.68) | SIRT1CA1CA2MAPTKDM4E | |
| SCHEMBL13082530 | 0.83 | CA1 (0.54) | CA1CA2MAPTKDM4ECA12 | |
| SCHEMBL5476111 | 0.83 | MAPT (0.68) | SIRT1CA1CA2MAPTKDM4E | |
| SCHEMBL8903151 | 0.82 | HSD17B1 (0.54) | SIRT1CA1CA2MAPTTPMT | |
| SCHEMBL1244094 | 0.82 | TPMT (0.65) | CA1CA2MAPTTPMTHTT | |
| SCHEMBL9389844 | 0.82 | TPMT (0.65) | CA1CA2MAPTTPMTHTT | |
| SCHEMBL3841301 | 0.82 | TPMT (0.65) | CA1CA2MAPTTPMTHTT | |
| SCHEMBL31257839 | 0.81 | L3MBTL1 (0.64) | SIRT1CA1CA2MAPTKDM4E | |
| SCHEMBL142204 | 0.81 | L3MBTL1 (0.64) | SIRT1CA1CA2MAPTKDM4E | |
| SCHEMBL6746043 | 0.79 | MAPK1 (0.63) | SIRT1CA1CA2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759367-B2 | COMPRISING THERMOSENSITIVE ELEMENT AND SUPPORT, THE THERMOSENSITIVE ELEMENT CONTAINING A SUBSTANTIALLY LIGHT-INSENSITIVE ORGANIC SILVER SALT, A 3,4-DIHYDROXYBENZENE COMPOUND, A BINDER | AGFA-GEVAERT (BE) | 2004-07-06 | — | — | US | claimed |
| US-20030054958-A1 | Thermographic recording material with improved print archivability without loss in printability | AGFA-GEVAERT (BE) | 2003-03-20 | — | — | US | claimed |
| EP-1245404-A1 | Thermographic recording material providing prints with good image density and tone having improved archivability | Agfa-Gevaert (BE) | 2002-10-02 | — | — | EP | claimed |
| US-6759367-B2 | COMPRISING THERMOSENSITIVE ELEMENT AND SUPPORT, THE THERMOSENSITIVE ELEMENT CONTAINING A SUBSTANTIALLY LIGHT-INSENSITIVE ORGANIC SILVER SALT, A 3,4-DIHYDROXYBENZENE COMPOUND, A BINDER | AGFA-GEVAERT (BE) | 2004-07-06 | — | — | US | disclosed |
| US-6693062-B2 | LIGHT INSENSITIVE ORGANIC SILVER SALTS, REDUCING AGENTS AND 1,2-DIHYDROXYBENZENE DERIVATIVE | AGFA-GEVAERT (BE) | 2004-02-17 | — | — | US | disclosed |
| US-20030054958-A1 | Thermographic recording material with improved print archivability without loss in printability | AGFA-GEVAERT (BE) | 2003-03-20 | — | — | US | disclosed |
| EP-1245404-A1 | Thermographic recording material providing prints with good image density and tone having improved archivability | Agfa-Gevaert (BE) | 2002-10-02 | — | — | EP | disclosed |