Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148202 | 0.84 | CYP19A1 (0.61) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL5951808 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL5952116 | 0.77 | ALDH1A1 (0.41) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL19772724 | 0.73 | MEN1 (0.58) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL11683527 | 0.73 | CYP19A1 (0.60) | MAPTALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL4169374 | 0.73 | ADRA1A (0.55) | MAPTKMT2AACHECYP19A1KDM4E | |
| SCHEMBL2345374 | 0.73 | ACHE (0.55) | MAPTACHEMAPK1CYP19A1METAP1 | |
| SCHEMBL30785363 | 0.73 | ACHE (0.55) | MAPTACHEMAPK1CYP19A1METAP1 | |
| SCHEMBL31751995 | 0.71 | CYP19A1 (0.59) | MAPTKMT2AACHECYP19A1KDM4E | |
| SCHEMBL29510831 | 0.71 | RAB9A (1.00) | MAPTALDH1A1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051957-A2 | A PROCESS FOR THE PREPARATION OF DONEPEZIL HYDROCHLORIDE | NEULAND LABORATORIES LTD. (IN) | 2011-05-05 | — | — | WO | disclosed |