Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28912140 | 0.71 | SMN1; SMN2 (0.33) | ALDH1A1KDM4EKMT2AMEN1RAB9A | |
| SCHEMBL9057850 | 0.69 | MYC (0.36) | KDM4C | |
| SCHEMBL550601 | 0.68 | IDO1 (0.39) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL8155087 | 0.66 | — | — | |
| SCHEMBL8537449 | 0.65 | LMNA (0.34) | ALDH1A1KDM4EMAPTHTTTSHR | |
| SCHEMBL9959991 | 0.64 | IDO1 (0.39) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL6731218 | 0.62 | MEN1 (0.46) | ALDH1A1KDM4EKMT2AMEN1HSD17B10 | |
| SCHEMBL29349590 | 0.61 | IDO1 (0.40) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL191346 | 0.61 | IDO1 (0.40) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL6538411 | 0.60 | CA12 (0.44) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160074400-A1 | WNT MODULATORS FOR THE PROTECTION, MITIGATION AND TREATMENT OF RADIATION INJURY | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160074400-A1 | WNT MODULATORS FOR THE PROTECTION, MITIGATION AND TREATMENT OF RADIATION INJURY | WNT3A, IWS1, WNT1 | KDM4C 3026/4885ALDH1A1 3033/4885KDM4E 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.