SCHEMBL17586140

SCHEMBL17586140

CCCCCCc1ccc(C)cc1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.47
MAPT P10636 3/20 0.47
TSHR P16473 2/20 0.47
TP53 P04637 2/20 0.47
HTT P42858 2/20 0.47
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX5 P09917 1/20 0.47
ALOX15 P16050 1/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
LIPG Q9Y5X9 1/20 0.41
CTRC Q99895 1/20 0.39
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
RAB9A P51151 2/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ALDH1A1 P00352 2/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19254235 0.92 CTRC (0.44) TYRMAPTTSHRTP53HTT
SCHEMBL13763448 0.85 TP53 (0.43) TYRMAPTTSHRTP53HTT
SCHEMBL9486060 0.85 TYR (0.50) TYRMAPTTSHRTP53HTT
SCHEMBL9921245 0.84 MAPT (0.38) MAPTTSHRCYP3A4KMT2ARAB9A
SCHEMBL11775528 0.83 ACLY (0.49) TYRMAPTTSHRTP53HTT
SCHEMBL16224885 0.83 ACLY (0.49) TYRMAPTTSHRTP53HTT
SCHEMBL2355598 0.82 TAAR1 (0.40) MAPTTSHRTP53MEN1CYP3A4
SCHEMBL24543287 0.81 GABRA1 (0.37) MAPTRAB9AATML3MBTL1NPC1
SCHEMBL29673152 0.81 GABRA1 (0.37) MAPTRAB9AATML3MBTL1NPC1
SCHEMBL10412816 0.81 TYR (0.50) TYRMAPTTSHRTP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2797880-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY BIO-PHARM SOLUTIONS CO LTD (KR) 2017-03-01 EP disclosed
US-20160075651-A1 GLYCOLIPID INHIBITION USING IMINOSUGARS UNITHER VIROLOGY, LLC (US) 2016-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160075651-A1 GLYCOLIPID INHIBITION USING IMINOSUGARS UGCG, UGGT1, DGAT1 TYR 2892/4885MAPT 1473/4885TSHR 3108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.