Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20848344 | 0.89 | POLB (0.40) | MAPTRAB9AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL20848342 | 0.85 | POLB (0.38) | MAPTRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL17589271 | 0.82 | L3MBTL1 (0.50) | MAPTSMN1; SMN2L3MBTL1POLBTDP1 | |
| SCHEMBL20848641 | 0.75 | LIPE (0.35) | MAPTL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL8587060 | 0.73 | MAPT (0.51) | MAPTRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL18257757 | 0.73 | LIPE (0.36) | MAPTMEN1KMT2AGAA | |
| SCHEMBL18257751 | 0.72 | GAA (0.36) | MAPTRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL10202259 | 0.72 | GAA (0.34) | MAPTSMN1; SMN2TP53GAA | |
| SCHEMBL24885613 | 0.71 | NAAA (0.44) | MAPTRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL832774 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190091338-A1 | MIKTO-ARM STAR POLYMERS FOR DELIVERY OF THERAPEUTIC AGENTS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190091338-A1 | MIKTO-ARM STAR POLYMERS FOR DELIVERY OF THERAPEUTIC AGENTS | COQ8A, COQ8B, STARD7 | MAPT 1748/4885RAB9A 3578/4885NPC1 2877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.