Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17615227 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2AMEN1RAB9A | |
| SCHEMBL17599982 | 0.84 | TDP1 (0.45) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL17615218 | 0.81 | CNR1 (0.45) | ALDH1A1KMT2AMEN1HPGDCNR2 | |
| SCHEMBL17616407 | 0.77 | ACP3 (0.53) | ALDH1A1KMT2ARAB9ANPC1CNR2 | |
| SCHEMBL17599932 | 0.77 | ACP3 (0.53) | ALDH1A1KMT2ARAB9ANPC1CNR2 | |
| SCHEMBL17615223 | 0.76 | CTSB (0.38) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL9658308 | 0.76 | KMT2A (0.61) | ALDH1A1KDM4EKMT2AMEN1RAB9A | |
| SCHEMBL14741002 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KDM4EKMT2AMEN1RAB9A | |
| SCHEMBL1515785 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KDM4EKMT2AMEN1RAB9A | |
| SCHEMBL11442217 | 0.74 | CYP2D6 (0.65) | ALDH1A1KDM4EKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160083409-A1 | METHOD FOR THE PREPARATION OF alpha-SUBSTITUTED ACRYL ALDEHYDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-03-24 | — | — | US | claimed |
| US-20160083409-A1 | METHOD FOR THE PREPARATION OF alpha-SUBSTITUTED ACRYL ALDEHYDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083409-A1 | METHOD FOR THE PREPARATION OF alpha-SUBSTITUTED ACRYL ALDEHYDES | ALDH1A1, ALDH3A1, ADH1A | ALDH1A1 1/4885KDM4E 856/4885KMT2A 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.