Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599982 | 0.89 | TDP1 (0.45) | MEN1KMT2ALMNAL3MBTL1CES2 | |
| SCHEMBL17615223 | 0.83 | CTSB (0.38) | CNR1CNR2MEN1KMT2ALMNA | |
| SCHEMBL17615227 | 0.81 | ALDH1A1 (0.46) | CNR2MEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL17599985 | 0.81 | ALDH1A1 (0.46) | CNR2MEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL17599932 | 0.81 | ACP3 (0.53) | CNR1CNR2KMT2AL3MBTL1CES2 | |
| SCHEMBL17616407 | 0.81 | ACP3 (0.53) | CNR1CNR2KMT2AL3MBTL1CES2 | |
| SCHEMBL17615173 | 0.78 | TACR1 (0.40) | CNR1CNR2MEN1KMT2ATDP1 | |
| SCHEMBL17615221 | 0.78 | MEN1 (0.39) | MEN1KMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL17616409 | 0.77 | L3MBTL1 (0.47) | MEN1KMT2ALMNAL3MBTL1TDP1 | |
| SCHEMBL17599963 | 0.77 | L3MBTL1 (0.47) | MEN1KMT2ALMNAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160083409-A1 | METHOD FOR THE PREPARATION OF alpha-SUBSTITUTED ACRYL ALDEHYDES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083409-A1 | METHOD FOR THE PREPARATION OF alpha-SUBSTITUTED ACRYL ALDEHYDES | ALDH1A1, ALDH3A1, ADH1A | CNR1 1284/4885CNR2 2578/4885MEN1 2483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.