Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17601996 | 0.87 | ABCB1 (0.40) | ABCB1ABCG2ACHECA2CA9 | |
| SCHEMBL17602006 | 0.86 | ACHE (0.54) | ABCB1ACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL15993833 | 0.83 | CHRNA7 (0.47) | ABCB1ACHECHRNA7 | |
| SCHEMBL15993797 | 0.77 | PDE4B (0.39) | ACHE | |
| SCHEMBL15993923 | 0.76 | ACHE (0.41) | ACHEMEN1KMT2A | |
| SCHEMBL22271888 | 0.76 | ACHE (0.59) | ABCB1ABCG2ACHEMAPTMEN1 | |
| SCHEMBL15993784 | 0.75 | ACHE (0.40) | ABCB1ACHEMEN1KMT2A | |
| SCHEMBL22271816 | 0.73 | CYP24A1 (0.44) | ABCB1LMNAALDH1A1 | |
| SCHEMBL17602007 | 0.72 | SLC6A3 (0.40) | ACHEMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL17602001 | 0.72 | ALOX15 (0.38) | ABCB1ACHELMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682954-B2 | Phenanthridine derivatives, preparation methods and uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2017-06-20 | — | — | US | claimed |
| US-20160083364-A1 | Phenanthridine Derivatives, Preparation Methods and Uses Thereof | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2016-03-24 | — | — | US | claimed |
| US-9682954-B2 | Phenanthridine derivatives, preparation methods and uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2017-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083364-A1 | Phenanthridine Derivatives, Preparation Methods and Uses Thereof | CTNNB1, WNT3A, WNT1 | ABCB1 25/4885ABCG2 78/4885ACHE 3841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.