Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472592 | 0.68 | ALDH1A1 (0.41) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL205562 | 0.66 | CYP2A6 (0.33) | ALDH1A1HSD17B10 | |
| SCHEMBL30286606 | 0.66 | CYP2A6 (0.33) | ALDH1A1HSD17B10 | |
| SCHEMBL816303 | 0.64 | KDM4E (0.37) | PARP1KDM4EALDH1A1GLAHPGD | |
| SCHEMBL12269543 | 0.59 | ALDH1A1 (0.41) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL3142984 | 0.57 | ALDH1A1 (0.39) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL13326153 | 0.57 | ALDH1A1 (0.39) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL4311602 | 0.57 | — | — | |
| SCHEMBL927812 | 0.57 | ALDH1A1 (0.50) | PARP1KDM4EALDH1A1GLAHPGD | |
| SCHEMBL2472141 | 0.56 | CA12 (0.32) | ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483280-B1 | FLUORESCENT NITROGENOUS BASE AND NUCLEOSIDES INCORPORATING SAME | GLEN RES CORP (US) | 2012-10-24 | — | — | EP | disclosed |
| US-7947459-B2 | Human Six Transmembrane Epithelial Antigen of the Prostate (STEAP) protein; folds in a \"serpentine\" manner into three extracellular and two intracellular loops; used for diagnosis and treatment of prostate cancer | AGENSYS, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| EP-1483280-A4 | FLUORESCENT NITROGENOUS BASE AND NUCLEOSIDES INCORPORATING SAME | GLEN RES CORP (US) | 2007-05-02 | — | — | EP | disclosed |
| US-7144995-B2 | Fluorescent nitrogenous base and nucleosides incorporating same | GLEN RESEARCH CORPORATION (US) | 2006-12-05 | — | — | US | disclosed |
| US-20060020113-A9 | Serpentine transmembrane antigens expressed in human cancers and uses thereof | HUBERT RENE S | 2006-01-26 | — | — | US | disclosed |
| US-20050004349-A1 | Serpentine transmembrane antigens expressed in human cancers and uses thereof | HUBERT RENE S (US) | 2005-01-06 | — | — | US | disclosed |
| EP-1483280-A2 | FLUORESCENT NITROGENOUS BASE AND NUCLEOSIDES INCORPORATING SAME | Glen Research Corporation (US) | 2004-12-08 | — | — | EP | disclosed |
| US-20040009933-A1 | Fluorescent nitrogenous base and nucleosides incorporating same | GLEN RESEARCH CORPORATION (US) | 2004-01-15 | — | — | US | disclosed |
| WO-2003077215-A2 | FLUORESCENT NITROGENOUS BASE AND NUCLEOSIDES INCORPORATING SAME | GLEN RESEARCH CORPORATION (US) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009933-A1 | Fluorescent nitrogenous base and nucleosides incorporating same | NUDT1, NT5C3B, NCL | PARP1 655/4885KDM4E 4706/4885ALDH1A1 3758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.