SCHEMBL176107

SCHEMBL176107

O=C(S)NCCc1c[nH]c2ccccc12

nearest known ligand 0.74

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.74
KMT2A Q03164 6/20 0.74
LMNA P02545 1/20 0.74
CYP1A2 P05177 1/20 0.74
PKM P14618 1/20 0.74
TSHR P16473 1/20 0.74
CYP2C19 P33261 1/20 0.74
BLM P54132 1/20 0.74
NPC1 O15118 2/20 0.70
RAB9A P51151 2/20 0.70
MMP9 P14780 1/20 0.70
AANAT Q16613 1/20 0.70
SIRT1 Q96EB6 1/20 0.67
FAAH O00519 1/20 0.65
MAPT P10636 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
MTNR1A P48039 3/20 0.64
POLB P06746 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6394942 0.86 MEN1 (0.76) MEN1KMT2ALMNACYP1A2PKM
SCHEMBL20227977 0.85 AANAT (0.75) MEN1KMT2ALMNACYP1A2PKM
SCHEMBL5841251 0.85 MEN1 (0.74) MEN1KMT2ALMNACYP1A2PKM
SCHEMBL627038 0.85 MEN1 (0.74) MEN1KMT2ALMNACYP1A2PKM
Nb-Acetyltryptamine SCHEMBL468850 0.85 MEN1 (1.00) MEN1KMT2ALMNACYP1A2PKM
SCHEMBL14700058 0.85 IDO1 (0.68) MEN1KMT2ALMNACYP1A2PKM
SCHEMBL5903804 0.84 AANAT (0.77) MEN1KMT2ALMNACYP1A2PKM
SCHEMBL10069200 0.84 AANAT (0.77) MEN1KMT2ALMNACYP1A2PKM
SCHEMBL7677886 0.84 MEN1 (0.84) MEN1KMT2ALMNACYP1A2PKM
Nb-Acetyltryptamine SCHEMBL29669230 0.84 MEN1 (0.97) MEN1KMT2ALMNACYP1A2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9918473-B2 Use of aryl carbamates in agriculture and other plant-related areas North Carolian State University (US) 2018-03-20 US disclosed
US-20160353739-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS UNIV NORTH CAROLINA STATE (US) 2016-12-08 US disclosed
US-9439436-B2 Use of aryl carbamates in agriculture and other plant-related areas NORTH CAROLINA STATE UNIVERSITY (US) 2016-09-13 US disclosed
US-9125408-B2 Use of aryl carbamates in agriculture and other plant-related areas NORTH CAROLINA STATE UNIVERSITY (US) 2015-09-08 US disclosed
US-8884022-B2 Inhibition of bacterial biofilms with aryl carbamates NORTH CAROLINA STATE UNIVERSITY (US) 2014-11-11 US disclosed
US-20130172187-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS NORTH CAROLINA STATE UNIVERSITY 2013-07-04 US disclosed
US-20130123225-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES NORTH CAROLINA STATE UNIVERSITY 2013-05-16 US disclosed
WO-2012030986-A2 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS NORTH CAROLINA STATE UNIVERSITY (US) 2012-03-08 WO disclosed
WO-2012006276-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES NORTH CAROLINA STATE UNIVERSITY (US) 2012-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130172187-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS CTRC, ACE, DDT MEN1 4199/4885KMT2A 522/4885LMNA 4641/4885
US-20160353739-A1 USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS CTRC, ACE, DDT MEN1 4199/4885KMT2A 522/4885LMNA 4641/4885
US-20130123225-A1 INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES PGLS, BLVRB, AADAC MEN1 4574/4885KMT2A 702/4885LMNA 4530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.