Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 5/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16053273 | 0.82 | PLD1 (0.39) | MAPTRAB9ADRD4DRD2PRCP | |
| SCHEMBL16053223 | 0.81 | NUDT1 (0.38) | MAPTRAB9ADRD4DRD2PRCP | |
| SCHEMBL16053274 | 0.69 | MAPT (0.76) | MAPTRAB9ADRD4DRD2KDM4E | |
| SCHEMBL16053272 | 0.62 | HTR3A (0.41) | MAPTRAB9ADRD4METAP2METAP1 | |
| SCHEMBL15767650 | 0.61 | NPC1 (0.48) | MAPTRAB9AKDM4EALDH1A1HTR2B | |
| SCHEMBL11397558 | 0.60 | METAP2 (0.77) | MAPTRAB9AKDM4EMETAP2METAP1 | |
| SCHEMBL14447536 | 0.59 | PARP1 (0.46) | MAPTRAB9AKDM4EHTR2B | |
| SCHEMBL7014462 | 0.58 | PLD1 (0.61) | MAPTRAB9AKDM4EALDH1A1CYP3A4 | |
| SCHEMBL30863815 | 0.58 | PLD1 (0.49) | MAPTKDM4EALDH1A1CYP3A4HTR2B | |
| SCHEMBL18124187 | 0.58 | ALDH1A1 (0.57) | MAPTKDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194388-A1 | IMIDAZO[4,5-C]PYRIDINE DERIVED SSAO INHIBITORS | Proximagen Limited (GB) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016042331-A1 | IMIDAZO[4,5-C]PYRIDINE DERIVED SSAO INHIBITORS | PROXIMAGEN LIMITED (GB) | 2016-03-24 | — | — | WO | disclosed |