SCHEMBL176121

SCHEMBL176121

S=C(SSC(=S)c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
MAPT P10636 3/20 0.44
PHGDH O43175 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HSP90AA1 P07900 1/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
KMT2A Q03164 1/20 0.42
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
TSHR P16473 2/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
MGLL Q99685 2/20 0.39
FAAH O00519 1/20 0.39
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11741123 0.87 ALDH1A1 (0.39) ALDH1A1MAPTPHGDHL3MBTL1HSP90AA1
SCHEMBL237352 0.85 SMN1; SMN2 (0.46) ALDH1A1MAPTL3MBTL1MEN1GAA
SCHEMBL1696237 0.85 ALDH1A1 (0.41) ALDH1A1MAPTPHGDHL3MBTL1HSP90AA1
SCHEMBL2106681 0.82 ALDH1A1 (0.44) ALDH1A1MAPTPHGDHL3MBTL1HSP90AA1
SCHEMBL23258761 0.81 CTSL (0.45) ALDH1A1MAPTL3MBTL1HSP90AA1MEN1
SCHEMBL163031 0.79 ALDH1A1 (0.39) ALDH1A1MAPTPHGDHL3MBTL1HSP90AA1
SCHEMBL12520176 0.78 ALDH1A1 (0.41) ALDH1A1MAPTPHGDHL3MBTL1HSP90AA1
SCHEMBL17621883 0.78 ALDH1A1 (0.41) ALDH1A1MAPTPHGDHL3MBTL1HSP90AA1
SCHEMBL2320794 0.78 ALDH1A1 (0.47) ALDH1A1MAPTPHGDHL3MBTL1HSP90AA1
SCHEMBL4370505 0.78 ALDH1A1 (0.41) ALDH1A1MAPTPHGDHL3MBTL1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 995 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574285-A Alcohol-soluble bio-based citronella polymer and preparation method and application thereof 武汉纺织大学 2026-02-27 CN claimed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
CN-115101808-B Janus brush-shaped polymer electrolyte and preparation and application thereof 华中科技大学 2025-05-09 CN claimed
WO-2025083111-A1 RUBBER COMPOSITIONS COMPRISING A SPECIFIC CROSSLINKING SYSTEM COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2025-04-24 WO claimed
CN-116462941-B Polyester composition and preparation method and application thereof 金发科技股份有限公司 2025-03-28 CN claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP claimed
CN-118767996-A Passivation type sulfided hydrogenation catalyst and preparation method and application thereof 国家能源投资集团有限责任公司 2024-10-15 CN claimed
WO-2024198980-A1 POLYESTER COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF 金发科技股份有限公司 2024-10-03 WO claimed
US-11886045-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-01-30 US claimed
WO-2004094523-A2 ELASTOMER COMPOSITION FOR POWER TRANSMISSION BELT TOOTH FACING DAYCO PRODUCTS, LLC (US) 2004-11-04 WO claimed
US-20040214675-A1 Elastomer composition for power transmission belt tooth facing DAYCO IP HOLDINGS, LLC 2004-10-28 US claimed
US-6372856-B1 2002-04-16 US claimed
US-6372856-B2 COMPRISING AN UNSATURATED NITRILE-CONJUGATED DIENE COPOLYMER RUBBER LATEX, A SULFUR-CONTAINING VULCANIZER, AT LEAST ONE VULCANIZATION ACCELERATOR SELECTED FROM DITHIOCARBAMIC ACID COMPOUNDS; NITROSAMINE FREE, FOR MEDICAL USE NIPPON ZEON CO., LTD. (JP) 2002-04-16 US claimed
EP-0446793-B1 Preparation process of polymeric solid electrolyte NIPPON OIL CO LTD (JP) 1995-08-02 EP claimed
US-5194490-A Polyelectrolytes for lithium cells NIPPON OIL CO., LTD. (JP) 1993-03-16 US claimed
US-5068982-A Rubber boot containing heat reflecting means SERVUS RUBBER COMPANY (US) 1991-12-03 US claimed
EP-0446793-A1 Preparation process of polymeric solid electrolyte Nippon Oil Co., Ltd. (JP) 1991-09-18 EP claimed
US-4284743-A BY VULCANIZATION ANIC S.P.A. (IT) 1981-08-18 US claimed
US-4001035-A COLORING COMPOSITION DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JA) 1977-01-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA ALDH1A1 1404/4885MAPT 1187/4885PHGDH 3766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.