Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176121 | 0.85 | ALDH1A1 (0.44) | MAPTFAAHMGLLALDH1A1L3MBTL1 | |
| SCHEMBL16300509 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTWDR5NCOA3FAAH | |
| SCHEMBL3282739 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTWDR5NCOA3FAAH | |
| SCHEMBL1478889 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTWDR5NCOA3FAAH | |
| SCHEMBL6721066 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTWDR5NCOA3FAAH | |
| SCHEMBL2838543 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTWDR5MGLLMMP3 | |
| SCHEMBL6721001 | 0.76 | CA12 (0.52) | SMN1; SMN2MAPTWDR5NCOA3ALDH1A1 | |
| SCHEMBL4253421 | 0.75 | RAB9A (0.52) | SMN1; SMN2MAPTWDR5NCOA3FAAH | |
| SCHEMBL6191835 | 0.74 | RAB9A (0.56) | SMN1; SMN2MAPTWDR5MGLLMMP3 | |
| SCHEMBL11741123 | 0.73 | ALDH1A1 (0.39) | MAPTFAAHMGLLALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745406-B2 | Curable composition | CEMEDINE CO., LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| EP-2412756-B1 | CURABLE COMPOSITION | CEMEDINE CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-2412756-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20120004371-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |