Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.63 |
| ▸ | ALB | P02768 | 2/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.63 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.63 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.63 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | HTR2B | P41595 | 1/20 | 0.63 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSPO | P30536 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1761298 | 0.84 | GABRA1 (0.65) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL1761290 | 0.83 | GABRA1 (0.68) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL27736733 | 0.82 | GABRA1 (0.67) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL2930904 | 0.82 | GABRA1 (0.70) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL1761296 | 0.81 | GABRA1 (0.58) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL1761287 | 0.80 | GABRA1 (0.74) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL2929266 | 0.80 | GABRA1 (0.74) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL1432425 | 0.80 | GABRA1 (0.53) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL1761268 | 0.80 | GABRA1 (0.63) | GABRA1GABRB2ALBOPRK1KCNH2 | |
| SCHEMBL2929147 | 0.79 | GABRB2 (0.73) | GABRA1GABRB2ALBOPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118256-A1 | IMIDAZO [1,2-A] PYRIDIN-3-YL-ACETIC ACID HYDRAZIDES, PROCESSES, USES AND COMPOSITIONS | FERRER INTERNACIONAL, S.A. | 2011-05-19 | — | — | US | claimed |
| US-7943611-B2 | Imidazo[1,2-A]pyridin-3-yl-acetic acid hydrazides, processes, for their preparation and pharmaceutical uses thereof | FERRER INTERNATIONAL, S.A. (ES) | 2011-05-17 | — | — | US | claimed |
| US-20090176777-A1 | Imidazo (1,2-a)Pyridin-3-YL-Acetic Acid Hydrazides, Proesses for Their Preparation and Pharmaceutical Uses Thereof | FERRER INTERNACIONAL, S.A. (ES) | 2009-07-09 | — | — | US | claimed |
| EP-1973907-B1 | IMIDAZO (1,2-A)PYRIDIN-3-YL-ACETIC ACID HYDRAZIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL USES THEREOF | FERRER INT (ES) | 2009-05-06 | — | — | EP | claimed |
| EP-1973907-A1 | IMIDAZO (1,2-A)PYRIDIN-3-YL-ACETIC ACID HYDRAZIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL USES THEREOF | Ferrer Internacional, S.A. (ES) | 2008-10-01 | — | — | EP | claimed |
| WO-2007077159-A1 | IMIDAZO (1,2-A)PYRIDIN-3-YL-ACETIC ACID HYDRAZIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL USES THEREOF | FERRER INTERNACIONAL, S.A. (ES) | 2007-07-12 | — | — | WO | claimed |
| EP-1803722-A1 | Imidazo[1,2-a]pyridin-3-yl-acetic acid hydrazides, processes for their preparation and pharmaceutical uses thereof | FERRER INTERNACIONAL, S.A. (ES) | 2007-07-04 | — | — | EP | claimed |
| US-20110118256-A1 | IMIDAZO [1,2-A] PYRIDIN-3-YL-ACETIC ACID HYDRAZIDES, PROCESSES, USES AND COMPOSITIONS | FERRER INTERNACIONAL, S.A. | 2011-05-19 | — | — | US | disclosed |
| US-20110118256-A1 | IMIDAZO [1,2-A] PYRIDIN-3-YL-ACETIC ACID HYDRAZIDES, PROCESSES, USES AND COMPOSITIONS | FERRER INTERNACIONAL, S.A. | 2011-05-19 | — | — | US | disclosed |
| US-20110118256-A1 | IMIDAZO [1,2-A] PYRIDIN-3-YL-ACETIC ACID HYDRAZIDES, PROCESSES, USES AND COMPOSITIONS | FERRER INTERNACIONAL, S.A. | 2011-05-19 | — | — | US | disclosed |
| US-7943611-B2 | Imidazo[1,2-A]pyridin-3-yl-acetic acid hydrazides, processes, for their preparation and pharmaceutical uses thereof | FERRER INTERNATIONAL, S.A. (ES) | 2011-05-17 | — | — | US | disclosed |
| US-7943611-B2 | Imidazo[1,2-A]pyridin-3-yl-acetic acid hydrazides, processes, for their preparation and pharmaceutical uses thereof | FERRER INTERNATIONAL, S.A. (ES) | 2011-05-17 | — | — | US | disclosed |
| US-20090176777-A1 | Imidazo (1,2-a)Pyridin-3-YL-Acetic Acid Hydrazides, Proesses for Their Preparation and Pharmaceutical Uses Thereof | FERRER INTERNACIONAL, S.A. (ES) | 2009-07-09 | — | — | US | disclosed |
| EP-1973907-B1 | IMIDAZO (1,2-A)PYRIDIN-3-YL-ACETIC ACID HYDRAZIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL USES THEREOF | FERRER INT (ES) | 2009-05-06 | — | — | EP | disclosed |
| EP-1973907-B1 | IMIDAZO (1,2-A)PYRIDIN-3-YL-ACETIC ACID HYDRAZIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL USES THEREOF | FERRER INT (ES) | 2009-05-06 | — | — | EP | disclosed |
| EP-1973907-A1 | IMIDAZO (1,2-A)PYRIDIN-3-YL-ACETIC ACID HYDRAZIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL USES THEREOF | Ferrer Internacional, S.A. (ES) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007077159-A1 | IMIDAZO (1,2-A)PYRIDIN-3-YL-ACETIC ACID HYDRAZIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL USES THEREOF | FERRER INTERNACIONAL, S.A. (ES) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007077159-A1 | IMIDAZO (1,2-A)PYRIDIN-3-YL-ACETIC ACID HYDRAZIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL USES THEREOF | FERRER INTERNACIONAL, S.A. (ES) | 2007-07-12 | — | — | WO | disclosed |
| EP-1803722-A1 | Imidazo[1,2-a]pyridin-3-yl-acetic acid hydrazides, processes for their preparation and pharmaceutical uses thereof | FERRER INTERNACIONAL, S.A. (ES) | 2007-07-04 | — | — | EP | disclosed |
| EP-1803722-A1 | Imidazo[1,2-a]pyridin-3-yl-acetic acid hydrazides, processes for their preparation and pharmaceutical uses thereof | FERRER INTERNACIONAL, S.A. (ES) | 2007-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118256-A1 | IMIDAZO [1,2-A] PYRIDIN-3-YL-ACETIC ACID HYDRAZIDES, PROCESSES, USES AND COMPOSITIONS | GABRA1, GABRA3, GABRA2 | GABRA1 1/4885GABRB2 9/4885ALB 867/4885 |
| US-20090176777-A1 | Imidazo (1,2-a)Pyridin-3-YL-Acetic Acid Hydrazides, Proesses for Their Preparation and Pharmaceutical Uses Thereof | GABRA3, GABRA1, GABRA2 | GABRA1 2/4885GABRB2 11/4885ALB 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.