SCHEMBL17614522

SCHEMBL17614522

CCn1c2ccc(C#N)cc2c2cc(-c3cc(-n4c5ccccc5c5ccccc54)cc(-n4c5ccccc5c5ccccc54)c3)ccc21

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 3/20 0.53
RORC P51449 9/20 0.50
MAPT P10636 4/20 0.47
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47
CASP1 P29466 1/20 0.47
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.45
HBB P68871 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NPY5R Q15761 3/20 0.44
LMNA P02545 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18010711 0.92 PTGER4 (0.52) PTGER4RORCMAPTKDM4EALDH1A1
SCHEMBL26452372 0.88 PTGER4 (0.40) PTGER4RORCKDM4E
SCHEMBL17721923 0.85 PTGER4 (0.38) PTGER4RORCKDM4E
SCHEMBL17721897 0.85 PTGER4 (0.38) PTGER4RORCKDM4E
SCHEMBL18010701 0.85 PTGER4 (0.52) PTGER4RORCMAPTKDM4EALDH1A1
SCHEMBL29643208 0.85 PTGER4 (0.63) PTGER4RORCMAPTKDM4EALDH1A1
SCHEMBL5892136 0.85 PTGER4 (0.63) PTGER4RORCMAPTKDM4EALDH1A1
SCHEMBL18540331 0.84 KDM4E (0.45) PTGER4RORCKDM4E
SCHEMBL18540338 0.84 KDM4E (0.45) PTGER4RORCKDM4E
SCHEMBL15250630 0.84 ATM (0.47) PTGER4RORCKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3061759-B1 NITRILE SUBSTITUTED DIBENZOFURANS IDEMITSU KOSAN CO (JP) 2019-12-25 EP disclosed
US-20190305228-A1 ORGANIC LIGHTEMITTING COMPOUND HAVING PHOSPHORESCENT CHARACTERISTIC AT ROOM TEMPERATURE, AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DEVICE INCLUDING THE ORGANIC LIGHTEMITTING COMPOUND RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVER SITY (KR) 2019-10-03 US disclosed
EP-3061759-A1 NITRILE SUBSTITUTED DIBENZOFURANS Idemitsu Kosan Co., Ltd (JP) 2016-08-31 EP disclosed
US-20160248026-A1 NITRILE SUBSTITUTED DIBENZOFURANS IDEMITSU KOSAN CO., LTD. (JP) 2016-08-25 US disclosed
US-20160087224-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-03-24 US disclosed
US-20160087227-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190305228-A1 ORGANIC LIGHTEMITTING COMPOUND HAVING PHOSPHORESCENT CHARACTERISTIC AT ROOM TEMPERATURE, AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DEVICE INCLUDING THE ORGANIC LIGHTEMITTING COMPOUND MAP1LC3C, MAP1LC3A, MAP1LC3B PTGER4 2603/4885RORC 410/4885MAPT 494/4885
US-20160248026-A1 NITRILE SUBSTITUTED DIBENZOFURANS DBF4, NXF1, NCF1 PTGER4 1001/4885RORC 4100/4885MAPT 2054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.