SCHEMBL17614550

SCHEMBL17614550

Cc1ccc(-c2cccc(OCc3c(C)cccc3-n3nnn(C)c3=O)c2)cn1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 2/20 0.39
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
FFAR1 O14842 1/20 0.36
ABL1 P00519 1/20 0.34
BCR P11274 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
PPARG P37231 1/20 0.33
EGLN1 Q9GZT9 2/20 0.33
NR1H4 Q96RI1 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
XBP1 P17861 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GRIN1 Q05586 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16206002 0.90 MAPT (0.41) SLC22A12PRMT5WDR77FFAR1ALDH1A1
SCHEMBL16206151 0.90 HSD17B1 (0.42) SLC22A12FFAR1PPARGEGLN1
SCHEMBL16206150 0.89 SLC22A12 (0.41) SLC22A12FFAR1NR1H4PTGER4
SCHEMBL16205967 0.89 SLC22A12 (0.42) SLC22A12FFAR1GABRA1GABRG2GABRB3
SCHEMBL17614582 0.89 GYS1 (0.34) SLC22A12FFAR1GABRA1PPARG
SCHEMBL17788124 0.88 MRGPRX4 (0.36) SLC22A12PRMT5WDR77ABL1BCR
SCHEMBL17614548 0.88 SLC22A12 (0.42) SLC22A12FFAR1ALDH1A1HPGDXBP1
SCHEMBL16206146 0.88 SLC22A12 (0.42) SLC22A12FFAR1NR1H4KMT2ANPSR1
SCHEMBL17614551 0.87 MRGPRX4 (0.43) SLC22A12FFAR1GABRG2GABRB3GABRA5
SCHEMBL17614547 0.87 PTGER4 (0.40) SLC22A12FFAR1ABL1BCRNR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9867372-B2 Tetrazolinone compound and use of same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-16 US disclosed
US-20160081339-A1 TETRAZOLINONE COMPOUND AND USE OF SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160081339-A1 TETRAZOLINONE COMPOUND AND USE OF SAME MT-CO1, SOD1, MT-CO2 SLC22A12 3344/4885PRMT5 1347/4885WDR77 2048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.