Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 15/20 | 0.81 |
| ▸ | RAB9A | P51151 | 15/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.81 |
| ▸ | HPGD | P15428 | 7/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.69 |
| ▸ | RELA | Q04206 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.65 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4343181 | 0.93 | NPC1 (0.94) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL22858502 | 0.90 | NPC1 (0.90) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL522555 | 0.90 | NPC1 (0.90) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL74999 | 0.90 | NPC1 (0.90) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL46424 | 0.90 | NPC1 (0.90) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL46426 | 0.90 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL13134570 | 0.89 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL2813678 | 0.89 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL17614682 | 0.88 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 | |
| SCHEMBL1105099 | 0.88 | NPC1 (0.85) | NPC1RAB9ASMN1; SMN2HPGDNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160087227-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-03-24 | — | — | US | disclosed |
| US-20160087227-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-03-24 | — | — | US | disclosed |