Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL889191 | 0.93 | DNM1 (0.49) | NAAADNM1GAAFAAHCASP2 | |
| SCHEMBL16638653 | 0.89 | NAAA (0.65) | NAAADNM1FAAHCASP2CNR1 | |
| SCHEMBL12792130 | 0.89 | NAAA (0.65) | NAAADNM1FAAHCASP2CNR1 | |
| SCHEMBL12792143 | 0.89 | NAAA (0.65) | NAAADNM1FAAHCASP2CNR1 | |
| SCHEMBL12791952 | 0.89 | NAAA (0.65) | NAAADNM1FAAHCASP2CNR1 | |
| SCHEMBL889199 | 0.87 | DNM1 (0.51) | NAAADNM1GAAFAAHCASP2 | |
| SCHEMBL16356885 | 0.87 | NAAA (0.41) | NAAADNM1GAAFAAHCASP2 | |
| SCHEMBL889316 | 0.86 | NAAA (0.61) | NAAADNM1FAAHCASP2CNR1 | |
| SCHEMBL889238 | 0.86 | NAAA (0.61) | NAAADNM1FAAHCASP2CNR1 | |
| SCHEMBL889317 | 0.86 | NAAA (0.61) | NAAADNM1FAAHCASP2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018080-B2 | Methods and compositions for treating cancer by targeting the CLEC2D-KLRB1 pathway | THE BROAD INSTITUTE, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-20240018552-A1 | NOVEL CRISPR ENZYMES AND SYSTEMS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2024-01-18 | — | — | US | disclosed |
| US-20160082126-A1 | NANOCOMPLEXES FOR DELIVERY OF SAPORIN | UNIV TUFTS (US) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12018080-B2 | Methods and compositions for treating cancer by targeting the CLEC2D-KLRB1 pathway | KLRK1, CD47, FCGR3B | NAAA 4336/4885DNM1 3022/4885GAA 2067/4885 |
| US-20240018552-A1 | NOVEL CRISPR ENZYMES AND SYSTEMS | CPSF1, CPSF6, CPN1 | NAAA 2743/4885DNM1 3631/4885GAA 353/4885 |
| US-20160082126-A1 | NANOCOMPLEXES FOR DELIVERY OF SAPORIN | SARNP, SAP30BP, SCP2 | NAAA 3052/4885DNM1 3713/4885GAA 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.