SCHEMBL17616611

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16273631	0.89	MAOB (0.47)	MAOBALDH1A1MAPTMAPK1CA12
	SCHEMBL17616632	0.85	MAOB (0.47)	MAOBALDH1A1MAPTMAPK1CA12
	SCHEMBL17616589	0.82	MAOB (0.47)	MAOBALDH1A1MAPTMAPK1CA12
	SCHEMBL16273630	0.81	MAOB (0.49)	MAOBALDH1A1MAPTMAPK1CA12
	SCHEMBL7268729	0.81	ALDH1A1 (0.53)	MAOBALDH1A1MAPTMAPK1CA12
	SCHEMBL17616582	0.78	NPC1 (0.48)	MAOBALDH1A1MAPTMAPK1CA12
	SCHEMBL7268739	0.78	MAOB (0.51)	MAOBALDH1A1MAPTMAPK1CA12
	SCHEMBL17616614	0.78	NPC1 (0.48)	MAOBALDH1A1MAPTMAPK1CA12
	SCHEMBL7266619	0.78	MAOB (0.48)	MAOBALDH1A1MAPTMAPK1CA12
	SCHEMBL17616647	0.77	TSHR (0.34)	MAOBALDH1A1MAPTTSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.