Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208194 | 0.75 | SMN1; SMN2 (0.62) | ALDH1A1L3MBTL1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL1102251 | 0.72 | KDM4E (0.62) | ALDH1A1L3MBTL1SMN1; SMN2POLBTSHR | |
| SCHEMBL12142432 | 0.69 | POLB (0.57) | ALDH1A1L3MBTL1SMN1; SMN2MAPTPOLB | |
| SCHEMBL13442408 | 0.69 | POLB (0.62) | ALDH1A1L3MBTL1NPSR1EGFRPOLB | |
| SCHEMBL9468298 | 0.69 | CDC25A (0.42) | ALDH1A1L3MBTL1ADORA3TBXA2RPTGS2 | |
| SCHEMBL22005102 | 0.69 | ACLY (0.46) | L3MBTL1MAPTNR1I2EGFRADRA2A | |
| SCHEMBL2833409 | 0.69 | KDM4E (0.49) | ALDH1A1L3MBTL1MAPTNPSR1POLB | |
| SCHEMBL4615101 | 0.68 | PTGS2 (0.38) | ALDH1A1L3MBTL1SMN1; SMN2MAPTNR1I2 | |
| SCHEMBL11605581 | 0.67 | CYP11B2 (0.38) | ALDH1A1L3MBTL1SMN1; SMN2MAPTTSHR | |
| SCHEMBL10515169 | 0.67 | CDC25A (0.45) | ALDH1A1L3MBTL1ADORA3TBXA2RPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160083402-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083402-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | NDC1, ELOC, UGT2B7 | ALDH1A1 1921/4885L3MBTL1 293/4885SMN1; SMN2 1952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.