SCHEMBL4631662

SCHEMBL4631662

COc1c(-c2ccccc2)oc2cc(O)cc(O)c2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 6/20 1.00
CYP3A4 P08684 3/20 0.83
CYP2D6 P10635 3/20 0.83
KDM4E B2RXH2 2/20 0.83
POLB P06746 2/20 0.83
APEX1 P27695 2/20 0.83
RECQL P46063 2/20 0.83
POLH Q9Y253 2/20 0.83
MCL1 Q07820 1/20 0.83
MEN1 O00255 3/20 0.75
KMT2A Q03164 3/20 0.75
MAPT P10636 2/20 0.75
MMP1 P03956 1/20 0.75
GAA P10253 1/20 0.75
HTT P42858 1/20 0.75
BLM P54132 1/20 0.75
HSD17B10 Q99714 1/20 0.75
TUBB4A P04350 1/20 0.72
TUBB P07437 1/20 0.72
TUBA3C P0DPH7 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18130384 0.91 ABCB1 (0.83) ABCB1CYP3A4CYP2D6KDM4EPOLB
Isokaempferide SCHEMBL1628023 0.91 POLH (1.00) ABCB1CYP3A4CYP2D6KDM4EPOLB
Isokaempferide SCHEMBL29721227 0.91 POLH (1.00) ABCB1CYP3A4CYP2D6KDM4EPOLB
SCHEMBL28664486 0.88 ABCB1 (0.79) ABCB1CYP3A4CYP2D6KDM4EPOLB
Ermanin SCHEMBL2875089 0.88 CYP3A4 (1.00) ABCB1CYP3A4CYP2D6KDM4EPOLB
SCHEMBL20100897 0.88 ABCB1 (0.79) ABCB1CYP3A4CYP2D6KDM4EPOLB
SCHEMBL11096105 0.87 POLH (0.83) ABCB1CYP3A4CYP2D6KDM4EPOLB
SCHEMBL15361036 0.87 POLH (0.83) ABCB1CYP3A4CYP2D6KDM4EPOLB
SCHEMBL3188065 0.87 POLH (0.83) ABCB1CYP3A4CYP2D6KDM4EPOLB
SCHEMBL28119670 0.86 ABCB1 (0.76) ABCB1CYP3A4CYP2D6KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051551-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2025-02-13 US claimed
CN-117561081-A Application of CYP450 inhibitor in inhibiting or killing mites and treating xerophthalmia 广州珍实视界生物医药科技有限公司 2024-02-13 CN claimed
CN-113069442-A Novel application of galangin and derivatives thereof 广东省农业科学院动物卫生研究所 2021-07-06 CN claimed
CN-112522195-A Micro RNA, inhibitor and application in-vitro culture of natural killer cells 张文化 2021-03-19 CN claimed
WO-1996031206-A2 FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS WARNER-LAMBERT COMPANY (US) 1996-10-10 WO claimed
US-12507703-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-12-30 US disclosed
CN-120585818-A Application of galangin-3-methyl ether in preparation of medicine for treating or preventing pathologic cardiac hypertrophy 江南大学 2025-09-05 CN disclosed
US-20250169516-A1 METHODS, DEVICES AND COMPOSITIONS FOR PRESERVING HUMAN MILK THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-05-29 US disclosed
US-12239142-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-03-04 US disclosed
US-20250051551-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2025-02-13 US disclosed
US-12163004-B2 Polymer composites WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-12-10 US disclosed
US-20240355451-A1 METHODS FOR IMPROVING GUT MICROBIOTA DIVERSITY NESTLE SA (CH) 2024-10-24 US disclosed
WO-2007110801-A2 COMPOSITIONS AND METHODS TO ADD VALUE TO PLANT PORDUCTS, INCREASING THE COMMERCIAL QUALITY, RESISTANCE TO EXTERNAL FACTORS AND POLYPHENOL CONTENT THEREOF LESCHOT SANHUEZA ANDRES ANTONI (CL) 2007-10-04 WO disclosed
US-20070232495-A1 Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof NAPPA ALVARO O 2007-10-04 US disclosed
CN-1958057-A Application of extractive of Daliangjiang, and application in medication HONGYI TECH CO LTD NANCHANG (CN) 2007-05-09 CN disclosed
US-20070098825-A1 Compositions containing Phaseolus vulgaris extract and Alpinia officinarum extract for the prevention and treatment of obesity and type II diabetes S.I.I.T. S.R.L. SERVISIO INTERNAZIONALE IMBA;;AGGI TERMOSALDANTI (IT) 2007-05-03 US disclosed
CN-1799616-A Gastric ulcer treatment medicine, its preparation process and application SHENZHEN DONGFANG TAIGE BIOPHA (CN) 2006-07-12 CN disclosed
EP-1212313-B1 7-CARBOXY-FLAVONE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USE NEGMA LERADS (FR) 2003-05-28 EP disclosed
WO-1996031206-A2 FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS WARNER-LAMBERT COMPANY (US) 1996-10-10 WO disclosed
WO-1996010408-A1 CARDIOACTIVE COMPOUNDS ISOLATED FROM WOODY PERENNIALS THE EXECUTIVE DIRECTOR OF THE WESTERN AUSTRALIAN DEPARTMENT OF CONSERVATION AND LAND MANAGEMENT (AU) 1996-04-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12507703-B2 Methods, devices and compositions for preserving human milk LPL, CEL, LPO ABCB1 4482/4885CYP3A4 1678/4885CYP2D6 1312/4885
US-20070232495-A1 Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof C5, PNN, NQO1 ABCB1 3107/4885CYP3A4 843/4885CYP2D6 2328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.