Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19658178 | 0.89 | ADORA3 (0.51) | ADORA3ADORA2AADORA2BKMT2ALMNA | |
| SCHEMBL20226169 | 0.87 | ADORA3 (0.44) | ALDH1A1ADORA3ADORA2AADORA2BPTGS2 | |
| SCHEMBL22749389 | 0.85 | KMT2A (0.49) | ALDH1A1KMT2AL3MBTL1LMNAMAPT | |
| SCHEMBL15896076 | 0.82 | ADORA3 (0.47) | ADORA3ADORA2AADORA2BKMT2AL3MBTL1 | |
| SCHEMBL15176978 | 0.82 | LMNA (0.51) | ALDH1A1ADORA3ADORA2AADORA2BKMT2A | |
| SCHEMBL10872844 | 0.82 | ALOX12 (0.54) | ALDH1A1ADORA3ADORA2AADORA2BKMT2A | |
| SCHEMBL10591633 | 0.81 | ADORA3 (0.46) | ADORA3ADORA2AADORA2BKMT2ALMNA | |
| SCHEMBL24969002 | 0.80 | L3MBTL1 (0.49) | ALDH1A1ADORA3ADORA2AADORA2BL3MBTL1 | |
| SCHEMBL17356718 | 0.79 | ADORA3 (0.47) | ALDH1A1ADORA3ADORA2AADORA2BKMT2A | |
| SCHEMBL13448336 | 0.78 | KMT2A (0.45) | ALDH1A1KMT2AKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240091315-A1 | XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME | AMUNIX PHARMACEUTICALS, INC. | 2024-03-21 | — | — | US | disclosed |
| US-11905548-B2 | Immobilized enzymatic reactor | WATERS TECHNOLOGIES CORPORATION (US) | 2024-02-20 | — | — | US | disclosed |
| CN-117462693-A | XTEN conjugate compositions and methods of making the same | 阿穆尼克斯运营公司 | 2024-01-30 | — | — | CN | disclosed |
| US-20230088954-A1 | IMMOBILIZED ENZYMATIC REACTOR | WATERS TECHNOLOGIES CORPORATION (US) | 2023-03-23 | — | — | US | disclosed |
| US-11434517-B2 | Immobilized enzymatic reactor | WATERS TECHNOLOGIES CORPORATION (US) | 2022-09-06 | — | — | US | disclosed |
| CN-114364701-A | Encapsulated protein 18 antibodies and methods of treating cancer | 加利福尼亚大学董事会 | 2022-04-15 | — | — | CN | disclosed |
| US-11220522-B2 | Cytotoxic platinum complex, its preparation and therapeutic use | CITY UNIVERSITY OF HONG KONG (HK) | 2022-01-11 | — | — | US | disclosed |
| EP-3421586-B1 | IMMOBILIZED ENYMATIC REACTOR | WATERS TECHNOLOGIES CORP (US) | 2021-10-27 | — | — | EP | disclosed |
| US-20210322518-A1 | XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME | AMUNIX PHARMACEUTICALS, INC. | 2021-10-21 | — | — | US | disclosed |
| CN-113004288-A | Method for preparing cytotoxic benzodiazepine derivatives | 伊缪诺金公司 | 2021-06-22 | — | — | CN | disclosed |
| EP-1322625-A2 | REAGENTS FOR LABELING BIOMOLECULES HAVING ALDEHYDE OR KETONE MOIETIES | Molecular Probes Inc. (US) | 2003-07-02 | — | — | EP | disclosed |
| EP-0938675-B1 | ANALYSIS OF CARBOHYDRATES | AMERSHAM PLC (GB) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002081738-A2 | SYSTEM AND METHOD FOR DETECTING AND QUANTIFYING NUCLEIC ACIDS USING COVALENT BINDING | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2002-10-17 | — | — | WO | disclosed |
| US-20020137068-A1 | Reagents for labeling biomolecules having aldehyde or ketone Moieties | MOLECULAR PROBES, INC. | 2002-09-26 | — | — | US | disclosed |
| WO-2002028841-A2 | REAGENTS FOR LABELING BIOMOLECULES HAVING ALDEHYDE OR KETONE MOIETIES | MOLECULAR PROBES, INC. (US) | 2002-04-11 | — | — | WO | disclosed |
| US-6294667-B1 | SEPARATION OF THE FLUORESCENTLY LABELLED CARBOHYDRATE SUBSTANCES, BY VIRTUE OF THEIR DIFFERENT CHARGE-TO-MASS RATIOS OR OTHER FACTORS, ENABLING A LARGER NUMBER OF DIFFERENT LABELLED CARBOHYDRATE SUBSTANCES TO BE SEPARATED | AMERSHAM INTERNATIONAL PLC | 2001-09-25 | — | — | US | disclosed |
| EP-0938675-A1 | ANALYSIS OF CARBOHYDRATES | AMERSHAM INTERNATIONAL plc (GB) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998015829-A1 | ANALYSIS OF CARBOHYDRATES | AMERSHAM INTERNATIONAL PLC (GB) | 1998-04-16 | — | — | WO | disclosed |
| US-5442045-A | Tracers in quantitative analysis, medical diagnosis; improved photostability | MOLECULAR PROBES, INC. (US) | 1995-08-15 | — | — | US | disclosed |
| US-5227487-A | Phthalein dye derivatives, fluorescent dyes | MOLECULAR PROBES, INC. (US) | 1993-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210322518-A1 | XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME | XPA, TXLNA, NGLY1 | ALDH1A1 3685/4885ADORA3 4284/4885ADORA2A 4421/4885 |
| US-20020137068-A1 | Reagents for labeling biomolecules having aldehyde or ketone Moieties | DERA, HLCS, CD44 | ALDH1A1 51/4885ADORA3 4628/4885ADORA2A 4590/4885 |
| US-11220522-B2 | Cytotoxic platinum complex, its preparation and therapeutic use | IDH1, SLC11A2, PDCD5 | ALDH1A1 1593/4885ADORA3 1986/4885ADORA2A 3519/4885 |
| US-20240091315-A1 | XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME | XPA, TXLNA, NGLY1 | ALDH1A1 3685/4885ADORA3 4284/4885ADORA2A 4421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.