Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17625664 | 0.89 | MAOA (0.39) | PDK2MEN1KMT2ARAB9AGAA | |
| SCHEMBL17625669 | 0.87 | MAOA (0.38) | PDK2MEN1KMT2ARAB9AGAA | |
| SCHEMBL17642439 | 0.78 | KIF11 (0.33) | PDK2RAB9A | |
| SCHEMBL17625665 | 0.77 | ALDH1A1 (0.35) | PDK2ALDH1A1F2 | |
| SCHEMBL20355847 | 0.75 | TSHR (0.36) | — | |
| SCHEMBL17625667 | 0.74 | HTT (0.44) | PDK2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL17629727 | 0.73 | KIF11 (0.41) | ST14PDK2MEN1KMT2ANPC1 | |
| SCHEMBL17625661 | 0.73 | PTPRZ1 (0.49) | MMP2MMP13PTPN1 | |
| SCHEMBL20355879 | 0.72 | ALDH1A1 (0.32) | ALDH1A1F2 | |
| SCHEMBL14216867 | 0.71 | MAOB (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | PROMERUS, LLC (US) | 2019-05-28 | — | — | US | disclosed |
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | PROMERUS, LLC (US) | 2018-07-05 | — | — | US | disclosed |
| US-20160083352-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | SUMITOMO BAKELITE CO., LTD. (JP) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083352-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | RDX, AOX1, ALDH1A2 | ST14 4579/4885PDK2 491/4885MEN1 3151/4885 |
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | ZYX, AOX1, RDX | ST14 4097/4885PDK2 1617/4885MEN1 2280/4885 |
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | ZYX, AOX1, RDX | ST14 4097/4885PDK2 1617/4885MEN1 2280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.